DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sff and Pim2

DIOPT Version :9

Sequence 1:	NP_648814.3	Gene:	sff / 39732	FlyBaseID:	FBgn0036544	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_613072.1	Gene:	Pim2 / 18715	MGIID:	97587	Length:	370	Species:	Mus musculus

Alignment Length:	277	Identity:	95/277 - (34%)
Similarity:	148/277 - (53%)	Gaps:	31/277 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREK------LSESVLMKVEREIAI 68
            :...|...|||...||||..|.|..|......::||||:|:|.:      :|:||...:  |:|:
Mouse    83 DRAAFEAEYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLGWSTVSDSVTCPL--EVAL 145

  Fly    69 MKLI----DHPHVLGLSDVYENKKYLYLILEH-VSGGELFDYLVKKGRLTPKEARKFFRQIISAL 128
            :..:    .||.|:.|.|.:|..:...|:||. :...:||||:.:||.|....:|.||.|:::|:
Mouse   146 LWKVGEGNGHPGVIRLLDWFETPEGFMLVLERPMPAQDLFDYITEKGPLGESCSRSFFTQVVAAV 210

  Fly   129 DFCHSHSICHRDLKPENLLLDE-KNNIKIADFGMASLQPAGSMLETS-----CGSPHYACPEVIR 187
            ..||:..:.|||:|.||:|:|. :.:||:.|||      :|::|...     .|:..|:.||.|.
Mouse   211 QHCHARGVVHRDIKDENILIDLCRGSIKLIDFG------SGALLHDEPYTDFDGTRVYSPPEWIS 269

  Fly   188 GEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEV 252
            ..:|....|.|||.||:||.::.|.:||:.|  :::||    ...|.|..|.|||.:|:|..:..
Mouse   270 RHQYHALPATVWSLGVLLYDMVCGDIPFERD--QEILE----AELHFPAHVSPDCCALIRRCLAP 328

  Fly   253 NPDRRLTLAEINRHPWV 269
            .|..|.:|.||...||:
Mouse   329 KPCSRPSLEEILLDPWM 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	93/269 (35%)
		S_TKc	18..269	CDD:214567	93/267 (35%)
		UBA_BRSK	298..350	CDD:270525
Pim2	NP_613072.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	61..83		95/277 (34%)
		PKc_like	90..346	CDD:304357	94/270 (35%)
		S_TKc	91..345	CDD:214567	93/267 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	349..370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000