Protein Alignment sff and aak-2

DIOPT Version :9

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_510710.2
• Gene: aak-2 / 181727
• WormBaseID: WBGene00020142
• Length: 626
• Species: Caenorhabditis elegans
• Alignment Length: 659
• Identity: 208/659 - (31%)
• Similarity: 294/659 - (44%)
• Gaps: 171/659 - (25%)

  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVL 78
            :|.|.|::|||.|..|.||:|:|.....|||:||:||:|: |..|:.|:.|||..:.|..|||::
 Worm    84 IGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHII 148

  Fly    79 GLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKP 143
            .|..|......:::|:|||||||||||:||.|||...|||:||:||||.:|:||.|.:.||||||
 Worm   149 RLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLKP 213

  Fly   144 ENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYAL 208
            |||||||:||:||||||::::...|..|.||||||:||.||||.|:.|.|.:.||||||||||||
 Worm   214 ENLLLDEQNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYAL 278

  Fly   209 LVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGG 273
            |.|.|||||:::..|..|:|.|||..|.|:.....:||..|:.|:|.:|.|:.::..|.|
 Worm   279 LCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVDPMKRATIKDVIAHEW----- 338

  Fly   274 KGELELELPMMEVVQTHVIP-----TATAVDPDVLNAICSLGCFKEKEKLIQELL--SSSHNTEK 331
               .:.:||      .::.|     .|:.||.:.:..:.....:...|:.:...|  ...|:...
 Worm   339 ---FQKDLP------NYLFPPINESEASIVDIEAVREVTEFQRYHVAEEEVTSALLGDDPHHHLS 394

  Fly   332 VIYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPR 396
            :.|.|:::.||..      ||.|:.|..|...|.|          |....|.:
 Worm   395 IAYNLIVDNKRIA------DETAKLSIEEFYQVTP----------NKGPGPVH------------ 431

  Fly   397 RQAFNFRSYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAGTRHS 461
                             |.|..:.:||  ||..:||..|:..|.|.:...|          ..|
 Worm   432 -----------------RHPERIAASV--SSKITPTLDNTEASGANRNKRA----------KWH- 466

  Fly   462 TYGDRDRSGHHSSVSRTPSHSSQKSIEG------DVVVVREP---------------RIERRDSL 505
             .|.|.:|.....:........|..:|.      .|:|.|:|               ::::|..|
 Worm   467 -LGIRSQSRPEDIMFEVFRAMKQLDMEWKVLNPYHVIVRRKPDAPAADPPKMSLQLYQVDQRSYL 530

  Fly   506 RQERGGGSPRDRGDCGIPPGSPGGNSSGSTSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGS 570
            ...:                |.....|||.|||.|.|
 Worm   531 LDFK----------------SLADEESGSASASSSRH---------------------------- 551

  Fly   571 PMMNNSSPGMPGSPCNTPGGQLWKTRLTNIKNSFLGSPRFHRRKMQVSADEVH--------LTPE 627
                 :|..||..|....|     ||.:::       |:....:..:...|||        :||.
 Worm   552 -----ASMSMPQKPAGIRG-----TRTSSM-------PQAMSMEASIEKMEVHDFSDMSCDVTPP 599

  Fly   628 SSPELTKRS 636
            .||...|.|
 Worm   600 PSPGGAKLS 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	135/253 (53%)
		S_TKc	18..269	CDD:214567	134/251 (53%)
		UBA_BRSK	298..350	CDD:270525	9/53 (17%)
aak-2	NP_510710.2	STKc_AMPK_alpha	84..339	CDD:270981	136/262 (52%)
		S_TKc	87..339	CDD:214567	135/259 (52%)
		UBA_AID_AMPKalpha	356..419	CDD:270521	15/68 (22%)
		AMPKA_C	462..624	CDD:213378	39/220 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100252
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810