Protein Alignment sff and unc-82

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001255294.1
• Gene: unc-82 / 177514
• WormBaseID: WBGene00006814
• Length: 1793
• Species: Caenorhabditis elegans
• Alignment Length: 838
• Identity: 211/838 - (25%)
• Similarity: 343/838 - (40%)
• Gaps: 174/838 - (20%)

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVLGLS 81
            :.:.|.||.|..|.|.|.......::||:|:|.:..: |::.|:::.|||.||..::||:::.:.
 Worm   297 FEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVRIRREIRIMSALNHPNIIQIY 361

  Fly    82 DVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 146
            :|:|||..:.|::|:.|||||:||:.:.|.|...|||:.||||.||:.:||.|.:.|||||.||:
 Worm   362 EVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYCHKHRVAHRDLKLENI 426

  Fly   147 LLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 211
            |||:.||.||||||:::.....::|.|.||||.||.||:|.|..|.|.:.|.||.|::||.|:.|
 Worm   427 LLDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPYKGPEVDCWSLGILLYTLVYG 491

  Fly   212 ALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGE 276
            ::|||..:..:::.::|||.:..|. .|.....|:|.|:.|||:||.|:.:|..|.|:      .
 Worm   492 SMPFDGRDFNRMVRQIKRGAYFEPE-TPSTASMLIRNMLRVNPERRATIFDIASHWWL------N 549

  Fly   277 LELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLS-----------SSHNTE 330
            ||..:|:::     .:|....:|...|..       :|:..::|:|..           ||....
 Worm   550 LEENMPVIQ-----ELPENQIIDHTPLTE-------REETMIVQDLADEQDVFMEFGHLSSETRR 602

  Fly   331 KVIYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTP 395
            |:..|    |.||:.|.|.:|.         ..|.||:.| .|..:.       |:||:..|...
 Worm   603 KIEDF----RIRRKEAEEFNDN---------SPVKPPKAR-KTDELT-------GKISKEQPEEM 646

  Fly   396 RRQAFNFRSYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAGTRH 460
            :....:.|..    ..::..|..|..             |.|:...:|..|.:.:
 Worm   647 KSAEKSLRGV----KEEKEKPKVVDP-------------NDPLERLRQIENRLGQ---------- 684

  Fly   461 STYGDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPG 525
                           ::....:::.|...:.|.::|  :::..|..|:     |.|       |.
 Worm   685 ---------------NKKDKEAAKTSARVETVKLKE--VKKEKSPEQQ-----PED-------PK 720

  Fly   526 SPGGNSSGSTSASPSV-----------HHRANSGPTIAISMFH-DPDSNSVVNPNGSPMMNNSSP 578
            :..|.|..:.|.:||.           ..|..:.|.:..|.:. :.||.::       :||....
 Worm   721 TARGTSKPADSRAPSFVPVKDRPETSEPERPRTRPHLTASAYRIETDSLNM-------LMNQVLE 778

  Fly   579 GMPGSPCNTPGGQLWKTRLTNIKNSFLGSPRFHRRKMQVSADEVHLTPESSPELTKRSWFGNLIT 643
            .|...|.|           .||.......|.:..|.|.....|..:..:..|...:.|......|
 Worm   779 QMEKGPVN-----------LNIIARIKAHPLYDTRPMVKELLESIIAAQPEPVQKQTSKVVEQQT 832

  Fly   644 TEKDETFTILVKGKPIATVKAHLIHAFLSMAELS-HSVVSPTSFRVEYKRNGNGPVMFQRHVKFQ 707
            ..:..|.|...|..|:......:......|.|.. |||           ..|..|.....|.:.|
 Worm   833 FSRQNTLTRKKKEDPLEEEIPEVPSPSRKMKERPWHSV-----------EVGFDPDEEPEHDRMQ 886

  Fly   708 VDISAICKQGDIADMLFALTFTLLSGNIRRFRRICEHIQSQVCSKRFPGPSSPPT-VTSVTQAVS 771
            ..|::...:..:.|..|.                 :....:...|:.|..|:|.| |..|.:..|
 Worm   887 ESIASNATEVTVQDTSFE-----------------DDSSDEEERKKTPVASTPKTPVLIVEKQES 934

  Fly   772 ESSSCGSVSSERLSYKRQVIENDMEN--DSIFSYKSGNGRRASTTNNNNANPVDIPGS 827
            .:::....|.|...|.    :.:||.  |.:......:.:.|....|..|||...|.|
 Worm   935 STNAEDEESDEGDDYS----DAEMEELADEVDKKGPSDSKLAPVVENLEANPPPDPSS 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	106/251 (42%)
		UBA_BRSK	298..350	CDD:270525	14/62 (23%)
unc-82	NP_001255294.1	STKc_NUAK	295..548	CDD:270975	106/251 (42%)