Protein Alignment sff and Nuak1

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_061507608.1
• Gene: Nuak1 / 1273841
• VectorBaseID: AGAMI1_000182
• Length: 3198
• Species: Anopheles gambiae
• Alignment Length: 908
• Identity: 238/908 - (26%)
• Similarity: 369/908 - (40%)
• Gaps: 197/908 - (21%)

  Fly    22 KTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVLGLSDVYE 85
            |.||:|..|.|:||::...|::||||.|.:.|: :|:.|:::.||:.||..:.||:::.:.:|:|
Mosquito    57 KKLGQGTYGKVQLGINKETGQEVAIKTIKKSKIETEADLIRIRREVQIMSSVQHPNIIHIYEVFE 121

  Fly    86 NKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDE 150
            |::.:.|::|..:||||:|||.::..|..:|||:.|||:.:|:.:||.|.|||||||.||:||||
Mosquito   122 NREKMVLVMEFAAGGELYDYLSERKVLAEEEARRIFRQVSTAIYYCHKHKICHRDLKLENILLDE 186

  Fly   151 KNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF 215
            ..|.||||||::::.....:|.|.||||.||.||:::|..|.|.:.|.||.||:||.|:.||:||
Mosquito   187 HGNAKIADFGLSNVFDEQRLLATFCGSPLYASPEIVKGTPYQGPEVDCWSLGVLLYTLVYGAMPF 251

  Fly   216 DDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGK------ 274
            |..|.::|::::.:|.:..|. .|.....|:|.|:.|.|..|..:.:|..|.||..|.:
Mosquito   252 DGANFKRLVKQISQGDYFEPK-KPSRASPLIREMLTVCPSHRANIEQICNHWWVNEGYEESCLDL 315

  Fly   275 -GELELELPM-MEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLL 337
             .||..:.|: ::|:.:...|:.||....|.|.        :::...::.:..||:...::
Mosquito   316 AEELANQTPVRLDVLLSLAPPSVTADQLLVGNG--------QEDAKAKDRIQRSHSMGSIV---- 368

  Fly   338 LERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNA--PSYGQISEGSPLTPRRQAF 400
                                  |:...:..|:.||.....|..|  |     |....:||...|.
Mosquito   369 ----------------------EMGGTEAERRILDMVAAGGEAALMP-----SPTRTITPAEAAT 406

  Fly   401 NFRSYSSTRNHQRRSPTTV-----TSSVR---SSSYHSPTRCNSPMSSAQQQANAISRPSSPAAG 457
            .....|.....:|:..|||     |.:|:   .:...||.:...|.....::|.....|:..||.
Mosquito   407 AAGVGSPQAQTKRKLETTVSTENATGAVKKKDKADPPSPAQARIPEDMDVEEAAVAGTPTQAAAD 471

  Fly   458 TRHSTYGDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERR-DSLRQERGGGSPRDRGDCG 521
            .:.:...........:..:.:.:..::...|...|:.....:|.. |.|..|.....|
Mosquito   472 EQAAEPVQPTAQEEATKPTDSAAQPNESKFEAQEVLEDLQNLENMCDELLLEAAHTQP------- 529

  Fly   522 IPPGSPGGNSSGSTSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSSPGMPGSPCN 586
             ||...|.|  |:|...||      |.|...:|..............|      :.|.:|.|...
Mosquito   530 -PPSEAGAN--GATEPPPS------SPPVKTVSSVRAKLEKLEKGEIG------AKPAVPSSTAP 579

  Fly   587 TPG-----GQLWKTRLT---NIKNSFLGSP-----RFHRRKMQVSADEVH----LTPESSPELTK 634
            .|.     |:...|.||   |..|:..|.|     ..||     ||..|.    |..||.....:
Mosquito   580 LPTVRKVFGKNKTTDLTTAINEVNARKGEPAPLAGSAHR-----SASSVERKNSLPDESLARTAE 639

  Fly   635 RSWFGNLITTEK------------DETFTILVKGKPIATVKAHLIHAFLSMAELSHS--VVSPTS 685
            |.....|.|.||            |:....::.|..:.|| .:....|.....||.|  ...|.:
Mosquito   640 RRKSRILETAEKFQQLNQQQPGGGDKFKKFVLPGGGVPTV-GNYKKEFERKTGLSTSSTFTKPPA 703

  Fly   686 FRVEYKRNGNG---------PVMFQRHVKFQVDISAICKQGDIADMLFALTFTLLSGNIRRFRRI 741
            ...:....|.|         |..|....|                            |:..:::
Mosquito   704 TTPQGATTGEGESGGSAPSTPPAFAGSAK----------------------------NLATYQQ- 739

  Fly   742 CEHIQSQVCSKRFPGPSSPP-TVTSVTQAVSESSSCGSVSSERLSYKRQVIENDMENDSIFSYKS 805
                |.|      .|..||| ..|.....|.||.|..||.|..|...|:.:||
Mosquito   740 ----QQQ------QGTDSPPLAATKSDDEVKESDSKSSVGSFSLEDARRSMEN------------ 782

  Fly   806 GNGRRASTTNNNNANPVD-IPGSPIAV-------RSNSETAEHERNRELQSERQATTMSGSAI 860
                  |....:.|.|.| .|.:|.|:       .|.|...:.||.|:|::.|:   :.|:||
Mosquito   783 ------SIAMLSRAKPNDSAPSTPTAIDQLCARTESVSMMEDSERERKLKNARE---IIGNAI 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	105/247 (43%)
		UBA_BRSK	298..350	CDD:270525	4/51 (8%)
Nuak1	XP_061507608.1	None