Protein Alignment sff and mark4

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_012824414.1
• Gene: mark4 / 100491038
• XenbaseID: XB-GENE-6042140
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 668
• Identity: 229/668 - (34%)
• Similarity: 324/668 - (48%)
• Gaps: 97/668 - (14%)

  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLIDHPHVLG 79
            ||.|||.:|:|||....|||..|.:.|::||||||::.:|:.|.|.|:.||:.|||.::||:::.
 Frog    48 VGNYRLLRTIGKGNFAKVKLARHVLTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK 112

  Fly    80 LSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPE 144
            |.:|.|.:|.||||:|:.||||:|||||..||:..||||..||||:||:.:||..:|.|||||.|
 Frog   113 LFEVIETEKTLYLIMEYASGGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAE 177

  Fly   145 NLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALL 209
            |||||.::||||||||.::....|..|:|.||||.||.||:.:|::|:|.:.||||.|||||.|:
 Frog   178 NLLLDSESNIKIADFGFSNEFTPGGKLDTFCGSPPYAAPELFQGKRYNGPEVDVWSLGVILYTLV 242

  Fly   210 VGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGK 274
            .|:||||..||::|.|:|.||.:.||.::..||:.:||..:.:||.:|.||.:|....|:..|..
 Frog   243 SGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEGVLRRFLVLNPSKRCTLDQIMNDKWMNIGFD 307

  Fly   275 GELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLE 339
            .: :|: |..|       |.....||..:..:..:|..:|:   |::.|||:...|.:..:|||.
 Frog   308 SD-DLK-PYKE-------PEEDNADPKRIEIMLEMGYSREE---IKDALSSNKYNEVMATYLLLG 360

  Fly   340 RKRRRPALED-DDEIAQKSRSELDA-------------------VDPPRKRLDTCRINGTNAPSY 384
            ||......|. .|.....|||.:.:                   ....|:..|.|  ....|||.
 Frog   361 RKPESEGGESRSDSTLSLSRSRVASDVTNGATKSSSVHSKNQRGYQRQRRHSDFC--GPAPAPSQ 423

  Fly   385 GQISE---------GSPLTPRRQAFNFRSYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSS 440
            .:.|.         |..|.|||.:      .|.....|..|   .||...|..|:|.:...|...
 Frog   424 AKRSPPGVGDDGAVGERLAPRRGS------GSVGGGSRPPP---PSSPMVSHAHNPNKAEIPEPR 479

  Fly   441 AQQQANAISRPSSPAAGTRHSTY--GDRDRSGHHSSV------SRTPSHSSQKSIEGDVVVVREP 497
            .:.....|:.|  |....|.:||  .||..|..||.:      |.|||.....|.....:..|.
 Frog   480 KEAPPTTINTP--PGVMGRRNTYVCTDRHSSERHSLLHNDKENSSTPSRPPALSPSTQSIAERS- 541

  Fly   498 RIERRDSLRQERGGGSPRDRGDCGIPPGSP----GGNSSGSTSASPSVHHRANSGPTIAISMFHD 558
            .:.|..::|....||..|||.....||.||    .|.:...|.|:.::..:..|..|..::
 Frog   542 SLSRGSNVRSTFHGGHVRDRRGQNPPPSSPTHPHEGLNQSRTRATSNLFSKLTSKLTRRVT---- 602

  Fly   559 PDSNSVVNPNGSPMMNNSSPGMPGS--PCNTPGGQLWKTRLTNIKNSFLGSPRFHRRKMQ---VS 618
            .:|..|..|.           :.||  |.|.          |:..:|.|..||..||..|   :.
 Frog   603 DESERVWRPE-----------VTGSYIPWNK----------TSANSSLLRPPRDVRRSSQHPPLQ 646

  Fly   619 ADEVHLTPESSPELTKRS 636
            ..|..:.|.|...:.:.|
 Frog   647 PTETSIAPNSPSSIGRPS 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	130/252 (52%)
		UBA_BRSK	298..350	CDD:270525	15/52 (29%)
mark4	XP_012824414.1	STKc_MARK	50..302	CDD:270974	129/251 (51%)
		UBA_MARK_Par1	323..361	CDD:270522	12/40 (30%)