Protein Alignment sff and nuak1

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_002931675.2
• Gene: nuak1 / 100491029
• XenbaseID: XB-GENE-980289
• Length: 660
• Species: Xenopus tropicalis
• Alignment Length: 695
• Identity: 190/695 - (27%)
• Similarity: 299/695 - (43%)
• Gaps: 172/695 - (24%)

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVLGLS 81
            |.|.:|||||..|.||..:....|:.||||.|.::|: .|..::.:.|||.||..::|||::.:.
 Frog    58 YELLETLGKGTYGKVKRAIERFSGRVVAIKSIRKDKIRDEQDMVHIRREIEIMSSLNHPHIIRIY 122

  Fly    82 DVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 146
            :|:|||..:.:|:|:.|.|||:||:.::.||:.:|.|.|||||:||:.:||.:.:.|||||.||:
 Frog   123 EVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENI 187

  Fly   147 LLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 211
            ||||..||||||||:::|......|:|.||||.||.||::.|..|.|.:.|.|:.||:||.|:.|
 Frog   188 LLDENGNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYG 252

  Fly   212 ALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGE 276
            .:|||..:.:.|:.::..|.:..| ..|.|.:.|:|.|:.|||:||.|:.:|..|.||....|
 Frog   253 TMPFDGFDHKNLIRQISSGEYREP-TQPSDARGLIRWMLMVNPERRATIEDIANHWWVNWSYK-- 314

  Fly   277 LELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLERK 341
                                       :::|.....::.|..:.......||....   ..||.:
 Frog   315 ---------------------------SSVCDCDVLRDSESPLLARFIDWHNRSTT---RQLEAE 349

  Fly   342 RRRPALEDDDEIA-------QKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPRRQA 399
            .:...|....|::       :||:.|.|.....:...|                |.|.:|..::.
 Frog   350 NKSKCLSKPSEMSLEQQRSLKKSKKESDIAQSLQDGAD----------------ETSSVTTSKRP 398

  Fly   400 FNFRSYSSTRNHQRRSPTT-----VTSSVRSSSYH----------SPTRCNS---PMSSAQQQAN 446
               :.....||...||.:.     |.|.|.|.:|:          ||.....   |:....:||.
 Frog   399 ---KGILKKRNGDYRSHSAGYIEGVVSPVLSPTYNTDDENGHIDLSPNSTQDLEVPIICDTKQAT 460

  Fly   447 AISRPSSPAAGTRHSTYGDRDRSGHHSSVSRTPS-----HSSQKSIEGDVVVVREPRIERRDSLR 506
            .:     |..|....|  .:..||::||..|:.|     :..::|| ...:|:.|.:.....||.
 Frog   461 PM-----PKKGILKKT--PQRESGYYSSPERSESSELLDNDGEESI-NSALVISETKRTVSHSLS 517

  Fly   507 QERGG---------------------GSPRDRGDCGIPPGSPGGNSSGSTSASPSVHHRANSGPT 550
            ..|.|                     |:..|....|:.||.  |.|            |:.|.|:
 Frog   518 YRRKGILKHNSKYSSNCIDLSVAGLTGASLDSMKEGVMPGE--GLS------------RSYSRPS 568

  Fly   551 IAISMFHDPDSNSVVNPNGSPMMNNSSPGMPGSPCNTPGGQLWKTRLTNIKNSFLGSPRFHRRKM 615
            ..||      .:|:::.:...::            ...||:..|.|:.:.
 Frog   569 SVIS------DDSILSNDSFDLL------------ELKGGRSNKQRIRSC--------------- 600

  Fly   616 QVSADEV-------HLTPESSPELTKRSWFGNLITTEKDETFTIL 653
             |||:.:       .|...|.|:..||  :.|...   |.:|::|
 Frog   601 -VSAENILYLQDFDGLQKSSRPQNLKR--YRNRFA---DNSFSLL 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	111/251 (44%)
		UBA_BRSK	298..350	CDD:270525	7/51 (14%)
nuak1	XP_002931675.2	STKc_NUAK	56..309	CDD:270975	111/251 (44%)