Protein Alignment sff and mark1

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_002936069.2
• Gene: mark1 / 100490022
• XenbaseID: XB-GENE-962867
• Length: 792
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 212/640 - (33%)
• Similarity: 323/640 - (50%)
• Gaps: 117/640 - (18%)

  Fly     8 TAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLI 72
            |.:....:|.|||.||:|||....|||..|.:.|::||:|||::.:|:.:.|.|:.||:.|||::
 Frog    50 TTDEQPHIGNYRLLKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114

  Fly    73 DHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 137
            :||:::.|.:|.|.:|.||||:|:.||||:|||||..||:..||||..||||:||:.:||...|.
 Frog   115 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIV 179

  Fly   138 HRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 202
            |||||.||||||...||||||||.::....|:.|:|.||||.||.||:.:|:||||.:.||||.|
 Frog   180 HRDLKAENLLLDADMNIKIADFGFSNEFTIGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 244

  Fly   203 VILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHP 267
            ||||.|:.|:||||..||::|.|:|.||.:.||.::..||::||:.::.:||.:|.:|.:|.:..
 Frog   245 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPVKRGSLEQIMKDR 309

  Fly   268 WVTAGGKGELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKV 332
            |:..|.:.| ||: |..|       |.....|...::.:.::|..:|:   |...:.:....|.:
 Frog   310 WMNVGYEDE-ELK-PYTE-------PEPDFNDTKRIDIMVTMGFSREE---INNAVVNQKYDEVM 362

  Fly   333 IYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPRR 397
            ..:|||.||  .|..|..:.::..:..       ||.| .:..:|.::.|        ||...:.
 Frog   363 ATYLLLGRK--PPEFEGTESLSSSNLC-------PRSR-PSSDLNNSSVP--------SPAHMKV 409

  Fly   398 QAFNFRSYSSTRNHQRRS-------PTTVT-------SSVRS----------SSYHSPTRCN--- 435
            |    ||.|:.:..:|.|       |.:|:       :||.|          |...|.|..|
 Frog   410 Q----RSISANQKQRRFSDHAGPSIPPSVSYTKRGQANSVESEQKEDWDKNGSRKLSSTMVNSKG 470

  Fly   436 ----SPMSSAQQQANAISRPSS--PAAG-TRHSTY-----GDR---DRSGHHSSV---------- 475
                ||::..:::.::....:|  |.:| ||.:||     .||   .::|..||:
 Frog   471 EVVASPLAGPERKKSSAGTSNSLFPGSGMTRRNTYVCERTTDRLTAVQNGKDSSLTEMSAGSTTS 535

  Fly   476 ------SRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGS 534
                  |..|.|....|..|..:.|..|.|  :|...     |.....|...:|..||..:|..:
 Frog   536 TASAVPSARPRHQKSMSASGHPIKVTLPTI--KDGTE-----GFRPSTGTQRVPATSPSAHSISA 593

  Fly   535 TSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSSP---GMPGSPCN 586
            |:...:...|.::    :.|.||           |..:.:..:.   |.|.||.:
 Frog   594 TTPDRTRFPRGST----SRSTFH-----------GEQLRDRRTATYNGPPASPAH 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	130/252 (52%)
		UBA_BRSK	298..350	CDD:270525	12/51 (24%)
mark1	XP_002936069.2	STKc_MARK	59..311	CDD:270974	129/251 (51%)
		UBA_MARK1	331..371	CDD:270588	8/42 (19%)
		MARK1-3_C	693..790	CDD:213381