DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sff and pimr52

DIOPT Version :9

Sequence 1:	NP_648814.3	Gene:	sff / 39732	FlyBaseID:	FBgn0036544	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	XP_021333990.1	Gene:	pimr52 / 100006411	ZFINID:	ZDB-GENE-070912-460	Length:	336	Species:	Danio rerio

Alignment Length:	248	Identity:	76/248 - (30%)
Similarity:	121/248 - (48%)	Gaps:	28/248 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LGKGQTGLVKLGVHCVIGKKVAIKIINRE----KLSESVLMKVEREIAIMKLIDH----PHVLGL 80
            ||:|..|.|..|:....|..||||.:::|    :|......::..|:|:|..:..    |.||.|
Zfish    86 LGRGGFGSVFAGIRRSDGLPVAIKYVSKEPTDTRLKVDGQGRLPLEVALMTRVSSAPVCPSVLQL 150

  Fly    81 SDVYENKKYLYLILEHVSG-GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPE 144
            .|.:::::...||||..:. .:|..:..:.|.|....|:|...|:|:||..|.|..:.|||:|||
Zfish   151 LDWFDHRRRYVLILERPAPCQDLQSFCEENGCLDEPLAKKVLVQLIAALKHCESRRVLHRDVKPE 215

  Fly   145 NLLLD-EKNNIKIADFGMASLQPAGSMLETS-----CGSPHYACPEVIRGEKYDGRKADVWSCGV 203
            |||:. :.::||:.|||      .|.:::.|     .|:|.:|.||..|..:|......|||.||
Zfish   216 NLLISTDSHDIKLLDFG------CGDLMKDSAYRYFAGTPAFAPPEWFRHHRYHASPLTVWSIGV 274

  Fly   204 ILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDR 256
            .||.:|....||  ...|::..|.:   .|.|..:..|  :.:....|..|::
Zfish   275 TLYNILCDCFPF--RGARRVTSKSR---LHFPRKLSTD--AAMTVYTEATPEQ 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	76/248 (31%)
		S_TKc	18..269	CDD:214567	76/248 (31%)
		UBA_BRSK	298..350	CDD:270525
pimr52	XP_021333990.1	PKc_like	79..308	CDD:328722	74/234 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000