Protein Alignment pHCl-1 and glrbb

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: XP_021336678.1
• Gene: glrbb / 445193
• ZFINID: ZDB-GENE-040801-106
• Length: 502
• Species: Danio rerio
• Alignment Length: 664
• Identity: 140/664 - (21%)
• Similarity: 229/664 - (34%)
• Gaps: 246/664 - (37%)

  Fly   334 SSSDKEILDLLLEKKRYDKRLLP-----PVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNV 393
            ::|...||:.||  ..||.|:.|     ||.|                             .||:
Zfish    61 ANSTSNILNKLL--ITYDPRIRPNFKGIPVED-----------------------------RVNI 94

  Fly   394 LLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALHHHD-----SIWTPDTYFI-- 451
            .:.|..|..|:::.|.|...|.|:||||||:.......|.|..    |     .:|.||.:|.
Zfish    95 FINSFGSIQETTMDYRVNIFLRQRWNDPRLRLPQDFKSDSLTV----DPKMFKCLWKPDLFFANE 155

  Fly   452 MHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIK 516
            ...:|.| :...:..|.|||||.:..:||..:.|||...|.:||.|..:|...:||..|....::
Zfish   156 KSANFHD-VTQENILLFIFRNGDVLISMRLSVTLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLQ 219

  Fly   517 YVWKNDEDTLRKSPSLTTLNAYLIKNQTTA---CDQ-NSWRGNYSCLQVELTFTRDRAYYFTTVF 577
            ::|::.:.......:|...:   ||.:...   |.: .:..|.|:|::|..|..|...:|...|:
Zfish   220 FMWQSGDPVQMDEIALPQFD---IKQEDIEYGNCTKYYAGTGYYTCVEVIFTLRRQVGFYMMGVY 281

  Fly   578 IPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCF 642
            .|.:::|..|:::||:..:|..|||.:|:.::|:..:......|.||.||.:.|:::|...|:.|
Zfish   282 APTLLIVVLSWLSFWINPDASAARVPLGILSVLSLSSECTSLASELPKVSYVKAIDIWLIACLLF 346

  Fly   643 IYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMG- 706
            .:|||:|:..|.                   |....|.:|......:|:...:...|||.:.:.
Zfish   347 GFASLVEYAVVQ-------------------VMLNSPKLLEAERAKIATKEKAEGKTPAKNTING 392

  Fly   707 -GATPMSSGTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARS 770
             |:||:
Zfish   393 MGSTPI----------------------------------------------------------- 398

  Fly   771 PSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRR---SVATSTP 832
                           |:      ||..||.|:.|          :...|.:.||.   |:..|.|
Zfish   399 ---------------HV------STLQVTETRCK----------KVCTSKSDLRTNDFSIVGSLP 432

  Fly   833 ALVVRIEAEIDPEAEDKPIQDMEMTERQLSLPLKPPRRKASRSNSPASVYSDAFENVEATPGEKR 897
                               :|.|::.                        .|.:
Zfish   433 -------------------RDFELSN------------------------FDCY----------- 443

  Fly   898 QNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPI--RVAKTIDVIARITFP 960
               |.|.|:       ||....:.:.||           :|..||.|:  ..||.||:.||..||
Zfish   444 ---GKPIEV-------GSAFSKSQAKNN-----------KKPPPPKPVIPSAAKRIDLYARALFP 487

  Fly   961 TAYAIFLIFFFVHY 974
            .::..|.:.::..|
Zfish   488 FSFLFFNVIYWSVY 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	64/243 (26%)
		Neur_chan_memb	578..>682	CDD:280999	27/103 (26%)
glrbb	XP_021336678.1	Neur_chan_LBD	53..501	CDD:332142	139/662 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.110