Protein Alignment pHCl-1 and nAChRalpha4

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001097669.2
• Gene: nAChRalpha4 / 40521
• FlyBaseID: FBgn0266347
• Length: 539
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 75/370 - (20%)
• Similarity: 143/370 - (38%)
• Gaps: 73/370 - (19%)

  Fly   338 KEILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPD 402
            |.:.|.||  ..|:|.:.|.||..|                       .|.|.:.:.|..|.
  Fly    13 KRLYDDLL--SNYNKLVRPVVNTTD-----------------------VLKVCIKLKLSQLI--- 49

  Fly   403 ESSLKYEV---EFLLNQQWNDPRLQYGNKSHYDFLNALH-HHDSIWTPD--TYFIMHGDFKDPII 461
            :.:||.::   ...:.|.|.|.:|::..| .|..::.|| ..|.||.||  .|....|:|:   :
  Fly    50 DVNLKNQIMTTNLWVEQSWYDYKLRWEPK-EYGGVHMLHVPSDHIWRPDIVLYNNADGNFE---V 110

  Fly   462 PMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYE--EAQIKYVWKN--- 521
            .:.....|:..|.:.:........||:..:..||||:..|.....|.:|:  :..::::.:.
  Fly   111 TLATKATIYSEGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFKVDLRHMDEQQGS 175

  Fly   522 -------DEDTLRKSPSLTTLNAYLIKNQT--TACDQNSWRGNYSCLQVELTFTRDRAYYFTTVF 577
                   |......|.....|....::|:.  |.||:     .|..:...:|..|...:|...:.
  Fly   176 NVVAVGVDLSEFYMSVEWDILEVPAVRNEKFYTCCDE-----PYLDITFNITMRRKTLFYTVNII 235

  Fly   578 IP--GIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCM 640
            ||  ||..:|  .:||:|..:: ..:|.:.::.:::....   |...:.::...:.:....|..:
  Fly   236 IPCMGISFLT--VLTFYLPSDS-GEKVTLSISILISLHVF---FLLVVEIIPPTSLVVPLLGKYL 294

  Fly   641 CFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRI 685
            .|....:...:||..|     :.||.:|   :|.|.::...:.|:
  Fly   295 IFAMILVSISICVTVV-----VLNVHFR---SPQTHKMAPWVKRV 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	52/247 (21%)
		Neur_chan_memb	578..>682	CDD:280999	20/105 (19%)
nAChRalpha4	NP_001097669.2	LIC	1..505	CDD:273305	75/370 (20%)
		Neur_chan_LBD	12..227	CDD:280998	53/250 (21%)
		Neur_chan_memb	234..505	CDD:280999	21/112 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100