Protein Alignment pHCl-1 and nAChRbeta1

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 99/513 - (19%)
• Similarity: 178/513 - (34%)
• Gaps: 143/513 - (27%)

  Fly   334 SSSDKE--ILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLL 396
            :|.|:|  :.||.   :.|:| |:.||                 ||..:     .:.|...:..:
  Fly    24 ASEDEERLVRDLF---RGYNK-LIRPV-----------------QNMTQ-----KVGVRFGLAFV 62

  Fly   397 SLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALH-HHDSIWTPDTYFIMHGD----- 455
            .|.:.:|.:...:....|...|.|.:||: :::.|..:..|. ..|.:|.||.....:.|
  Fly    63 QLINVNEKNQIMKSNVWLRLVWYDYQLQW-DEADYGGIGVLRLPPDKVWKPDIVLFNNADGNYEV 126

  Fly   456 -FKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVW 519
             :|..::       |:..|.:.:........||...:..||||...|.....|.::...|:....
  Fly   127 RYKSNVL-------IYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLAL 184

  Fly   520 KNDEDTLRKSP-------SLTTLNAYLIKNQTTACDQNSWRGNYS-CLQVELTF----TRDRAYY 572
            .|:::.:..|.       .:..:.|||          |.:.|:.: ..:.::||    .|...:|
  Fly   185 YNNKNFVDLSDYWKSGTWDIIEVPAYL----------NVYEGDSNHPTETDITFYIIIRRKTLFY 239

  Fly   573 FTTVFIPGIILVTSSFITFWLEWNAVPA----RVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMN 633
            ...:.:|.:::.....:.|:|     ||    :|.:|::.:|:...........||..| |....
  Fly   240 TVNLILPTVLISFLCVLVFYL-----PAEAGEKVTLGISILLSLVVFLLLVSKILPPTS-LVLPL 298

  Fly   634 VWDGVCMCFI---YASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRI-------GVI 688
            :...:...||   .:.|:..:.:|:..|             .|.|.|:|..:..|       .:.
  Fly   299 IAKYLLFTFIMNTVSILVTVIIINWNFR-------------GPRTHRMPMYIRSIFLHYLPAFLF 350

  Fly   689 LASP----LASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEF--FGGG------M 741
            :..|    |......|.|||.....| |.|:||..             |:..  .||.      |
  Fly   351 MKRPRKTRLRWMMEMPGMSMPAHPHP-SYGSPAEL-------------PKHISAIGGKQSKMEVM 401

  Fly   742 RWQEAH------------GGIIGAAVQNLRARSIKRKAARSPSTSISPHPSGRPTEHI 787
            ...:.|            ||.:|.      ....:|::..|.|..:||..| :.||.:
  Fly   402 ELSDLHHPNCKINRKVNSGGELGL------GDGCRRESESSDSILLSPEAS-KATEAV 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	46/248 (19%)
		Neur_chan_memb	578..>682	CDD:280999	21/110 (19%)
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:273305	99/513 (19%)
		Neur_chan_LBD	28..236	CDD:280998	47/251 (19%)
		Neur_chan_memb	243..498	CDD:280999	49/250 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100