Protein Alignment pHCl-1 and lgc-38

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001355511.1
• Gene: lgc-38 / 3565717
• WormBaseID: WBGene00017389
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 118/520 - (22%)
• Similarity: 192/520 - (36%)
• Gaps: 184/520 - (35%)

  Fly   297 LMLCYLTTA-------------STAAATQSETGALDKHPIHGIDWSKFDESSSDKE-----ILDL 343
            |::.|:||.             :..|:|:...|.               ||:.:.|     :||.
 Worm     9 LLIGYVTTEHPPLMKSDKLIEYAPQASTEPTLGG---------------ESNENLENNVTRLLDK 58

  Fly   344 LLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRG-TLTVNVNVLLLSLASPDESSLK 407
            |:..  :|:|:                         ||:..| .:.||:...:.::::..|.|:.
 Worm    59 LIAS--HDRRI-------------------------RPNYGGPPIEVNITAHVTTISAVSEVSMD 96

  Fly   408 YEVEFLLNQQWNDPRLQYGNKSHYDFLNALHHHDSIWTPDTYF-----------IMHGDFKDPII 461
            |.::..|.|.|.||||.:.:.........:....:||||||:|           ..|..|
 Worm    97 YTLDLYLRQIWKDPRLAWESDVEDSLTIGIDMVKTIWTPDTFFPNEKKSFFHEATSHNSF----- 156

  Fly   462 PMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKN----- 521
                 |||..:|.:..::|..:..:|..|||.||.|..:|:..:||..|....|.|.|..
 Worm   157 -----LRIDNHGNVLRSIRLTVTANCPMSLHTFPLDRQECALEVESYGYSTKDIIYHWHGTNAVT 216

  Fly   522 -DEDT------------LRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLQVELTFTRDRAYYF 573
             ||:.            :.::.||:|                   ||||.|.....|.|:..:|.
 Worm   217 IDENVHLAHFTIGEHKHIERTISLST-------------------GNYSRLTAYFLFKRNIGFYL 262

  Fly   574 TTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGV 638
            ..::.|..::|..|:::|||...||.|||.|||||:|...|......::||.||.:.:::|:.||
 Worm   263 IQIYFPSSLIVVISWVSFWLNREAVQARVAIGVTTVLTMTTLMTSTNASLPKVSYVKSLDVFLGV 327

  Fly   639 CMCFIYASLLEFVCVNYV----------------------------------------------G 657
            |...::|||||:..:.|:                                              .
 Worm   328 CFFIVFASLLEYAAIGYLMKRNRSVPAASPVQYYETEEFFEIQCHPKFVRGAINYCDGVLKREAS 392

  Fly   658 RKRPL------------HNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMGGATP 710
            ||:..            :|:.:||.:..|.||:| :||.:      |:......|.....|...|
 Worm   393 RKKSRNRRDSSMKNYQNNNIHHRPSDGHVDQRIP-LLSMV------PMPPIPFKPQNGAWGKVRP 450

  Fly   711  710
             Worm   451  450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	59/262 (23%)
		Neur_chan_memb	578..>682	CDD:280999	41/161 (25%)
lgc-38	NP_001355511.1	LIC	42..476	CDD:273305	111/487 (23%)
		LGIC_ECD_GABAR_RDL-like	76..257	CDD:349809	51/209 (24%)
		Cys-loop	177..191	CDD:349809	7/13 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910