Protein Alignment pHCl-1 and lgc-58

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001368738.1
• Gene: lgc-58 / 191637
• WormBaseID: WBGene00001587
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 680
• Identity: 151/680 - (22%)
• Similarity: 262/680 - (38%)
• Gaps: 188/680 - (27%)

  Fly   333 ESSSDKEI---LDLLLEKKR--YDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLT-VNV 391
            |:|..:.:   ||.||...|  ||.: .|||.                      |::..:| |.:
 Worm    19 EASRSEPVPIYLDNLLNAGRQVYDNQ-SPPVQ----------------------HDKEEVTVVEL 60

  Fly   392 NVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLN---ALHHHDSIWTPDTYF--I 451
            .:.:..::|....::.::::....|.|.||||.: |::....:.   .||   .:|.||.||  .
 Worm    61 AMYIEGMSSFRTQTMDFQLDVYFQQFWRDPRLAH-NETRRVLVKDKAVLH---KMWKPDVYFANA 121

  Fly   452 MHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIK 516
            ...:|.:...| :|.:.|..:|:|.|..|..:::.|..:|..:|.|..:|...:.|.:|...|:.
 Worm   122 RIAEFHEVTQP-NFLVWIQPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSYAYTTEQLV 185

  Fly   517 YVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLQVELTFTRDRAYYFTTVFIPGI 581
            ..||.|| .:.::|::...:.:::......||.|...|.:||:..|....|:..::....::|..
 Worm   186 IKWKEDE-PITRNPNIAMSDMHIVDLYPGLCDGNYSTGTWSCVTAEFFVKREITHHVMQSYVPTT 249

  Fly   582 ILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYAS 646
            ::|..|:.:|||:..||||||.:.:||:|...|.:|..|..||.||.:.|::||.|.||.|::..
 Worm   250 LIVVISWFSFWLDVEAVPARVSLAITTLLTLSTQANAARMALPEVSYMKAIDVWMGACMMFVFGV 314

  Fly   647 LLEFVCVNYVGRK-RPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMGGATP 710
            ::||..|||..|: |..|.                  :...:::||.|.|
 Worm   315 MIEFTIVNYAQRQGRKWHR------------------TDAEIVMASSLES--------------- 346

  Fly   711 MSSGTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQN--LRARSIKRKAARSPST 773
            :.||......|                          .|.:||..::  ||.|:.:|
 Worm   347 VKSGNAEKKPS--------------------------RGDLGAHARHLFLRLRTNER-------- 377

  Fly   774 SISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAES--------STKLRRSVATS 830
                       :|:.|:|                      ||:...        |.....|.:..
 Worm   378 -----------QHLVEDP----------------------PEQIAMNDTAYDTVSQAYSNSFSDE 409

  Fly   831 TPALVVRIEAEIDPEAEDKPIQD---MEMTERQLSLPLKPPRRKASRSNSPAS--VYSDAFENVE 890
            ..|.||:     .|:.||...|:   .|..|..||        :..:.:.||.  .:.:..||..
 Worm   410 EAAPVVQ-----PPQNEDAEAQEEVWAEQKETNLS--------EVWKESDPAERLAHWNEKENDA 461

  Fly   891 ATP----GEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPI------ 945
            ::|    |......||..::        .|..|..|:.......:...|::|.:....:
 Worm   462 SSPLMGNGRAHVRYGAAEKM--------KNRKCNDSSRKKEKWSSAIKQIQKHKRNGSVFGKIAG 518

  Fly   946 -RVAKTIDVIARITFPTAYAIFLIFFFVHY 974
             ..||.||..:|..||..:.||.:.::::|
 Worm   519 RNRAKKIDQTSRWIFPLTFIIFNLTYWIYY 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	56/238 (24%)
		Neur_chan_memb	578..>682	CDD:280999	37/104 (36%)
lgc-58	NP_001368738.1	LIC	30..548	CDD:273305	148/667 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020