Protein Alignment pHCl-1 and lgc-41

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001360683.1
• Gene: lgc-41 / 183331
• WormBaseID: WBGene00008022
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 635
• Identity: 147/635 - (23%)
• Similarity: 250/635 - (39%)
• Gaps: 141/635 - (22%)

  Fly   371 DMATNQNARRPHNRGT--LTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDF 433
            ::....|.|.|....:  |.|.:.:.|.||.:...|.:.::|:..:...|.||||.: |.|.|..
 Worm    33 NLLQQSNTRPPTANASVPLGVKLGMYLESLGNFRSSEMSFDVDLYVYMSWQDPRLAH-NFSDYVL 96

  Fly   434 LNALHHHDSIWTPDTYF--IMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPF 496
            :|.......||.||.||  .....|::..:| :|.|.:..:||:.|:.|..|.::|..:|..:|.
 Worm    97 INNDEIRKQIWLPDLYFANARQASFQEVTVP-NFNLFVAPDGTVAYSCRCTLTVACSLNLRYYPM 160

  Fly   497 DDPKCSFSMESISYEEAQIKYVW-------KNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRG 554
            |...||..:.|.:|...|:...|       .|:|..|.:.......|||...:...|..:||::.
 Worm   161 DQQLCSIRVLSYAYIAKQVNVTWFDKNPVRFNEEIGLPEFQIEHVSNAYCNGSYQYALTENSYKS 225

  Fly   555 -NYSCLQVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNG 618
             ::|||...|..:|...|.....:||..::|..|:::||::..||||||.:..||:::..|..||
 Worm   226 DDFSCLSGNLFLSRSIGYNLVQSYIPTGLIVMISWVSFWIDRRAVPARVTLSFTTLVSLTTLGNG 290

  Fly   619 FRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRK--------RPLHNVVYRPGENPVT 675
            .|..||.||...|:::|.|.||.|::.:||||..:|...||        :.:.:||       :|
 Worm   291 LRFGLPQVSYAKAIDLWYGACMFFVFCALLEFATINSYMRKSEKFDSMAKKMQSVV-------LT 348

  Fly   676 QRLPAVLSRIGVILASPLASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEFFGGG 740
            .|....|.| |:           ..:|.:.|||.  .:...|.:....|..|.
 Worm   349 GRTRDYLVR-GI-----------KESMRIAGGAA--GNVVDALNDDWCTYSTE------------ 387

  Fly   741 MRWQEAHGGIIGAAVQNL-RARSIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVK 804
             ..:::...::|...:.. .|.|.:|...|...|..||...|:|         .:...:.|.::|
 Worm   388 -NGRKSFSAMVGDIFERAGNAISPRRNRYRGLKTEKSPRGYGKP---------DTVQDILSERIK 442

  Fly   805 FKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEIDPEAEDKPIQDMEMTERQLSLPLKPPR 869
            |.|.                              |.:.|.:.:|:             :|
 Worm   443 FIDN------------------------------EFDFDTKEDDE-------------IP----- 459

  Fly   870 RKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTT---CGGSN-------SPCTHSAN 924
                 .|...|:|    :||..    ::..|.:.:|....:|   ..|:|       .....|..
 Worm   460 -----GNMAMSIY----DNVSC----RKDEADSSSEETKFSTKPKRNGTNGTRKYIDKSLNQSGQ 511

  Fly   925 NGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHY 974
            |.......:.|:......|.:::.|:    .|..||.|:.::.:|::.:|
 Worm   512 NDSLIVATYFQISANHSRHALKIDKS----CRYLFPAAFLLWNVFYWWYY 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	57/206 (28%)
		Neur_chan_memb	578..>682	CDD:280999	39/111 (35%)
lgc-41	NP_001360683.1	LIC	41..>332	CDD:273305	92/292 (32%)
		LGIC_TM	<527..557	CDD:365787	7/33 (21%)
		TM4 helix	530..554	CDD:349850	7/27 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020