Protein Alignment pHCl-1 and Gabra4

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001345970.1
• Gene: Gabra4 / 14397
• MGIID: 95616
• Length: 578
• Species: Mus musculus
• Alignment Length: 695
• Identity: 161/695 - (23%)
• Similarity: 240/695 - (34%)
• Gaps: 218/695 - (31%)

  Fly   333 ESSSDKE--------ILDLLLEKKRYDKRLLPPVNDEDFC-----CGLQSPDMATNQNARRPHNR 384
            ::|.|::        |||.||:  .||.||.|.....| |     |.|..              |
Mouse    36 QNSKDEKLCPENFTRILDSLLD--GYDNRLRPGFGGTD-CFKTCKCALSV--------------R 83

  Fly   385 -----------GTLT-VNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNAL 437
                       |.:| |..::.:.|.....:..::|.::....|.|.|.||:|........||.:
Mouse    84 LWSACLFVEILGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNM 148

  Fly   438 HHHDSIWTPDTYF------IMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPF 496
             ....:|||||:|      :.|.     :...:...||.|||||.|.||..:...|...|..||.
Mouse   149 -MVTKVWTPDTFFRNGKKSVSHN-----MTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPM 207

  Fly   497 DDPKCSFSMESISYEEAQIKYVW-KNDEDTLRKSPSLTTLNAYLIKNQTTACDQ-NSWRGNYSCL 559
            |...|.....|.:|.::::.|.| |..|.::......::|..|.:..||.:.:. .|..|.|..:
Mouse   208 DGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVM 272

  Fly   560 QVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLP 624
            .|.....|...|:....:||.|:.|..|.::||:...:||||.:.|:||:|...|.|...|.:||
Mouse   273 TVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLP 337

  Fly   625 VVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAV-------- 681
            .||..|||:.:..||..|::::|:||..|||      ..|:..:..:..:::..|.|
Mouse   338 KVSYATAMDWFIAVCFAFVFSALIEFAAVNY------FTNIQMQKAKKKISKPPPEVPAAPVLKE 396

  Fly   682 ------LSRIGVILASPLASAAATPAMSMMGGATPM---SSGTPAA-SSSVATPGTPRITDPEEF 736
                  |......|.....:.|...:.|.:...|.:   ||.|.|. .||.|||.....:.|..|
Mouse   397 KHTETSLQNTHANLNMRKRTNALVHSESDVKSRTEVGNHSSKTSAVQESSEATPKAHLASSPNPF 461

  Fly   737 FGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPHPSG--RPTEHIYEEPGGSTSGVT 799
                               ....|......|||..|::.||.|.|  ||          ::.|..
Mouse   462 -------------------SRANAAETMSAAARGLSSAASPSPHGTLRP----------ASLGSA 497

  Fly   800 STKVKFKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEIDPEAEDKPIQDMEMTERQLSLP 864
            ||:..|...|           .:::.:|.|
Mouse   498 STRPAFGSRL-----------GRIKTTVNT----------------------------------- 516

  Fly   865 LKPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCAT 929
                              :.|..||.|||...     ||
Mouse   517 ------------------TGAAGNVSATPPPP-----AP-------------------------- 532

  Fly   930 ETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHY 974
                       ||.....:| ||..|||.||..:..|.:.::|.|
Mouse   533 -----------PPSGSGTSK-IDKYARILFPVTFGAFNMVYWVVY 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	65/260 (25%)
		Neur_chan_memb	578..>682	CDD:280999	37/117 (32%)
Gabra4	NP_001345970.1	Neur_chan_LBD	13..565	CDD:332142	160/693 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910