Protein Alignment pHCl-1 and gabrb3

DIOPT Version :9

• Sequence 1: NP_001261898.1
• Gene: pHCl-1 / 39730
• FlyBaseID: FBgn0264908
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001096164.1
• Gene: gabrb3 / 100124708
• XenbaseID: XB-GENE-6030743
• Length: 475
• Species: Xenopus tropicalis
• Alignment Length: 656
• Identity: 131/656 - (19%)
• Similarity: 228/656 - (34%)
• Gaps: 239/656 - (36%)

  Fly   338 KEILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPD 402
            ||.:|.||  |.||.||.|     ||                   ....:.|.:|:.:.|:....
 Frog    38 KETVDKLL--KGYDIRLRP-----DF-------------------GGSPVAVGMNIDIASIDMVS 76

  Fly   403 ESSLKYEVEFLLNQQWNDPRLQY-GNKSHYDFLNALHHHDSIWTPDTYFI------MHG-DFKDP 459
            |.::.|.:.....|.|.|.||.| |...:....|.:  .|.:|.|||||:      :|| ..|:.
 Frog    77 EVNMDYTLTMYFQQYWRDKRLAYTGIPLNLTLDNRV--ADQLWVPDTYFLNDKKSFVHGVTVKNR 139

  Fly   460 IIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDED 524
            :|.:|      .:||:.|.:|.....:|...|..:|.|:..|:..:||..|....|::.|...::
 Frog   140 MIRLH------PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWLGGDN 198

  Fly   525 TLR-----KSPSLTTLNAYLI-KNQTTACDQNSWRGNYSCLQVELTFTRDRAYYFTTVFIPGIIL 583
            .:.     :.|..:.::..|: ||...|      .|:|..|.:.....|:..|:....::|.|::
 Frog   199 AVTGVERIELPQFSIMDHKLVSKNVVFA------TGSYPRLSLSFKLKRNIGYFILQTYMPSILI 257

  Fly   584 VTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLL 648
            ...|:::||:.::|..|||.:|:||:|...|.:...|.|||.:..:.|::::...|..|::.:||
 Frog   258 TILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALL 322

  Fly   649 EFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMGGATPMSS 713
            |:..|||:
 Frog   323 EYAFVNYI--------------------------------------------------------- 330

  Fly   714 GTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPH 778
                                  |||.|.:.|                :.:..|:|:| :...|..
 Frog   331 ----------------------FFGRGPQMQ----------------KKLAEKSAKS-NKDHSKF 356

  Fly   779 PSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEID 843
            .|.|...|         ..:..|.::..:|:   ...|..:|....|:.|||
 Frog   357 ESNRVDAH---------GNILLTTLEIHNEV---TGNEITTSVSDARNSATS------------- 396

  Fly   844 PEAEDKPIQDMEMTERQLSLPLKPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVA 908
              .::..||..:.:..:.||    .||.|.|::.|..
 Frog   397 --FDNSGIQYRKQSTARDSL----GRRTADRNHPPKK---------------------------- 427

  Fly   909 CTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIA-----RITFPTAYAIFLI 968
                       ||              :|::.....|::....||.|     ||.||..:::|.:
 Frog   428 -----------TH--------------LRRRSSQLKIKIPDLTDVNAIDRWSRIVFPITFSLFNL 467

  Fly   969 FFFVHY 974
            .::::|
 Frog   468 IYWLYY 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pHCl-1	NP_001261898.1	Neur_chan_LBD	338..566	CDD:280998	60/241 (25%)
		Neur_chan_memb	578..>682	CDD:280999	27/103 (26%)
gabrb3	NP_001096164.1	LIC	11..473	CDD:273305	130/654 (20%)
		Neur_chan_LBD	41..243	CDD:280998	59/241 (24%)
		Neur_chan_memb	250..470	CDD:280999	68/399 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910