DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment meru and Rassf7

DIOPT Version :9

Sequence 1:	NP_001246779.1	Gene:	meru / 39727	FlyBaseID:	FBgn0052150	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_080162.3	Gene:	Rassf7 / 66985	MGIID:	1914235	Length:	359	Species:	Mus musculus

Alignment Length:	415	Identity:	81/415 - (19%)
Similarity:	141/415 - (33%)	Gaps:	116/415 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 EIPIWMDDGEARYVSGVTNKTTCDDIIKALIDDELRNGNGFYCGNNPKDGGQRKTAAASRDYSDY 188
            |:.:|: ||..|.|.||:.:|||.:::.||                         |.|......:
Mouse     9 ELKVWV-DGIQRVVCGVSEQTTCQEVVIAL-------------------------AQAIGQTGRF 47

  Fly   189 IITESWGGIERCYDGNMAILP------VWRAWSRVHNELRI-------SLKHRDSF-------RD 233
            ::      ::|..:....:||      ......:..|:::.       ||..|.|.       |.
Mouse    48 VL------VQRLREKERQLLPQECPVGAQATCGQFANDVQFVLRRTGPSLSGRPSSDNCPPPERC 106

  Fly   234 PLAMQLVPHSQSATGFSMYKWLKKLLHLKKGKKTP--PKPTKTPPKVPNKLKEKRVHGQKQTMTN 296
            |:...|.|...:..|....|.|...|...|...:|  |:|......:|:...:          ..
Mouse   107 PVRASLPPKPSAIPGREPRKALTFNLRCPKLVPSPSIPEPAALVGPIPDGFAD----------LQ 161

  Fly   297 DLVLVIMPDQLYRGTENTAKSKLYKLAENRVSKQRHRRRSRHEITKASVETFRTAIPSECNNNNY 361
            ||.|     ::.|.||.......::....|  :|...|..:..:...|..|...|...|
Mouse   162 DLEL-----RIQRNTEELGHEAFWEQELQR--EQAREREGQARLQALSAATAEHAARLE------ 213

  Fly   362 NVNNCIRRRKDKPLRNSVRYKLASLHADMNVRYEK--EHALTRQLSEMCRLYRLQNERYKGPEME 424
                            ::..:..:|.|::.:..|.  ..:.|...:|..|......||: ..||:
Mouse   214 ----------------ALDAQACALEAELRLAAEAPGPPSATASAAERLRQDLATQERH-SLEMQ 261

  Fly   425 LSVGQLQQNIEAYAEDIIKTE-HELLELKNEIKHDISLINNLKRLTLEESEADAACKKGAAKITH 488
            .::..:.|.:|| ||..::.: .||.||..|::.     .||::...:         .|||....
Mouse   262 GTLALVSQALEA-AEHALQAQAQELEELNRELRQ-----CNLQQFIQQ---------TGAALPPP 311

  Fly   489 PLQENENTPQ----VAKNTQEMQFV 509
            |.|.:...|.    ::.|..|:|.|
Mouse   312 PPQLDRTIPSTQDLLSPNRGELQGV 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
meru	NP_001246779.1	None
Rassf7	NP_080162.3	RA_RASSF7	8..90	CDD:340552	19/112 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..123		9/35 (26%)
		SMC_prok_B	<158..>334	CDD:274008	43/230 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15286
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000