DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment meru and Rassf9

DIOPT Version :9

Sequence 1:	NP_001246779.1	Gene:	meru / 39727	FlyBaseID:	FBgn0052150	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_075248.1	Gene:	Rassf9 / 65053	RGDID:	621329	Length:	435	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	88/416 - (21%)
Similarity:	151/416 - (36%)	Gaps:	124/416 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 APPHRQACKNKHGRENGNAGQASRRHRSISLYGVNSTVEQGHKEIPIWMDDGEARYVSGVTNKTT 145
            ||..|...|.:|            ::||     ....::...|||.:|:.. |.:.|.|:|.:||
  Rat     2 APFGRNLLKTRH------------KNRS-----PTKDMDPEEKEIVVWVCQ-EEKIVCGLTKRTT 48

  Fly   146 CDDIIKALIDDELRNGNGFYCGNNPKDGGQRKTAAASRDYSDYIITESWGGIERCYDGNMAILPV 210
            ..|:|:||:::            :....|:::......  |||.|.|.|.|.||.......||.:
  Rat    49 SIDVIQALLEE------------HEATFGEKRFLLGKA--SDYCIVEKWRGSERALPPLTRILKL 99

  Fly   211 WRAWSRVHNELRISLKHRDSFRD-PL----AMQLVPHSQSATGFSMYKWLKKLLHLKKGKKTPPK 270
            |:||......::..|...|:|.. ||    ..:||.:::.....|...::|.|
  Rat   100 WKAWGDEQPNMQFVLVKTDAFLPVPLWRTAETKLVQNNEKPWELSPANYMKTL------------ 152

  Fly   271 PTKTPPKVPNKLKEKRVHGQKQTMTNDLVLVIMPDQLYRGTENTAKSKLYKLAENRVSKQRHRRR 335
                ||.     |:||:                           .:....|||:.|.....|.|.
  Rat   153 ----PPD-----KQKRI---------------------------VRKTFRKLAKIRQDTGSHDRD 181

  Fly   336 SRHEITKASVETFRTAIPSECNNNNYNVNNCIRRRKDKPLRNSVRYKLASLHADM----NVRYEK 396
            :...:....:            :.::.::..::|.|:  |...:....|.:|.|.    ...|.:
  Rat   182 NMECLVHLII------------SQDHTIHQQVQRMKE--LDMEIEKCEAKIHLDRIGNDGADYVQ 232

  Fly   397 EHALTRQLSEMCRLYRLQNERYKGPEMELS----VGQLQQNIEAYAEDIIKTEHELLELKNEIK- 456
            |..|..:.||..:....|:|..:..| :|:    |.||::.::.|...|.|..   .|::.|:|
  Rat   233 EAYLMPRSSEEEQKLDFQSEDNQTLE-DLNDGEGVSQLEEQLQYYRALIDKLS---AEIEREVKG 293

  Fly   457 --HDISLINNLKRLTLEESEADAACK 480
              .|.|          |:.|..|||:
  Rat   294 AGTDGS----------EDMEGAAACE 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
meru	NP_001246779.1	None
Rassf9	NP_075248.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		7/36 (19%)
		RA	23..118	CDD:214612	30/109 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	371..423
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003658
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830