Protein Alignment meru and RASSF10

DIOPT Version :9

• Sequence 1: NP_001246779.1
• Gene: meru / 39727
• FlyBaseID: FBgn0052150
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001073990.2
• Gene: RASSF10 / 644943
• HGNCID: 33984
• Length: 507
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 95/522 - (18%)
• Similarity: 171/522 - (32%)
• Gaps: 160/522 - (30%)

  Fly   118 VEQGHKEIPIWMDDGEARYVSGVTNKTTCDDIIKALIDD------ELRNGNGFYCGNNPKDGGQR 176
            ::...|:|.:|:.. |.:.|||::.:|||.|:::.|::|      ..|.........:|...|:.
Human     1 MDPSEKKISVWICQ-EEKLVSGLSRRTTCSDVVRVLLEDGCRRRRRQRRSRRLGSAGDPHGPGEL 64

  Fly   177 KTAAASRDYSD---------------YIITESWGGIERCYDGNMAILPVWRAWSRVHNELRISLK 226
            .......|..|               |.|.|.|.|.||.......||.:|.||......:|..|.
Human    65 PEPPNEDDEDDDEALPQGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWAAWGEEQENVRFVLV 129

  Fly   227 HRDS----------------------------FRDPLAMQLVPHSQSATGFSMYKWLKKL--LHL 261
            ..::                            .|..|||     :|......:.|..:||  |:.
Human   130 RSEASLPNAGPRSAEARVVLSRERPCPARGAPARPSLAM-----TQEKQRRVVRKAFRKLAKLNR 189

  Fly   262 KKGKKTPPKPTKTPPKVPNKLKEK-RVH--GQKQTMTNDLVLVIMPDQLYRGTENTAKSKLYKLA 323
            ::.::||...:.|.....:..... |.|  ...:.|...:.||:..|       :|.:.::.:|.
Human   190 RRQQQTPSSCSSTSSSTASSCSSSPRTHESASVERMETLVHLVLSQD-------HTIRQQVQRLH 247

  Fly   324 E------NRVSKQRHRRRSRHEITKASVETFRTAIPSECNNNNYNVNNCIRRRKDKPLRNSVRYK 382
            |      :..:|....|..||.:.... :|:......|.:.:         |..::|  ..|..:
Human   248 ELDREIDHYEAKVHLDRMRRHGVNYVQ-DTYLVGAGIELDGS---------RPGEEP--EEVAAE 300

  Fly   383 LASLHADMNVRYEKEHALTRQLSEMC-RLYRLQNERYK--------------------------- 419
            .....|...:..|.:.|...:|:..| .|.|||.:|.:
Human   301 AEEAAAAPPLAGEAQAAALEELARRCDDLLRLQEQRVQQEELLERLSAEIQEELNQRWMRRRQEE 365

  Fly   420 ------------GPEMELSVGQ----------------LQQNIEAYAEDIIKTEHELLELKNEIK 456
                        ||:.||.:.|                |..::||...|:..::.:....|.|::
Human   366 LAAREEPLEPDGGPDGELLLEQERVRTQLSTSLYIGLRLNTDLEAVKSDLDYSQQQWDSKKRELQ 430

  Fly   457 HDISLINNLKRLTLEESEADA-----------AC-------KKGAAKITHPLQENENTPQVAKNT 503
            ..:..::.|: ||:....|..           ||       .:|.||......|:.:|...:.::
Human   431 GLLQTLHTLE-LTVAPDGAPGSGSPSREPGPQACADMWVDQARGLAKSGPGNDEDSDTGLSSMHS 494

  Fly   504 QE 505
            |:
Human   495 QD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
meru	NP_001246779.1	None
RASSF10	NP_001073990.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..80		5/33 (15%)
		UBQ	<88..132	CDD:294102	14/43 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	185..222		6/36 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..507		9/53 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003658
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.830