Protein Alignment DCP2 and DCP2

DIOPT Version :9

• Sequence 1: NP_001246776.1
• Gene: DCP2 / 39722
• FlyBaseID: FBgn0036534
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_014281.1
• Gene: DCP2 / 855605
• SGDID: S000005062
• Length: 970
• Species: Saccharomyces cerevisiae
• Alignment Length: 665
• Identity: 150/665 - (22%)
• Similarity: 265/665 - (39%)
• Gaps: 170/665 - (25%)

  Fly   213 ILDDLASRFIINVPDMELNNLIRMCFQIELAHWFYLDFFCAPESGEDGETPKCVQRKLPSVGIKQ 277
            ||:||..|||||.|:.:|:::.|..|..|.|.|||.||.            |.:...|||:.||.
Yeast    18 ILEDLLVRFIINCPNEDLSSVERELFHFEEASWFYTDFI------------KLMNPTLPSLKIKS 70

  Fly   278 FAMQLFQHIPFLNKHFGTVDQILDEWKNYKLSVPTYGAILVSEDHNHCLLVQSYFARNSWGFPKG 342
            ||..:.:..|.:.|....||:.|.::..||.|:|..||.:.:|:.:..||||. ...:||.||:|
Yeast    71 FAQLIIKLCPLVWKWDIRVDEALQQFSKYKKSIPVRGAAIFNENLSKILLVQG-TESDSWSFPRG 134

  Fly   343 KINENEDPAHCATREVYEETGFDITDLIDANDYIEAFINYQYTRLYVVRNIPMDTQFAPRTRNEI 407
            ||:::|:...|..|||.||.|||:||.||.|.:||..|..:..:::::..:.....|.|:.||||
Yeast   135 KISKDENDIDCCIREVKEEIGFDLTDYIDDNQFIERNIQGKNYKIFLISGVSEVFNFKPQVRNEI 199

  Fly   408 KCCDWFRIDALPVNKNDAISKAKLGKTSNSFFMIMPFVKRLKKWV-NDRKAGIEPRRRKFSGQQS 471
            ...:||  |...::|.       :.|::..:::|...::.|..|: :.|:...|.:.:.::.:|
Yeast   200 DKIEWF--DFKKISKT-------MYKSNIKYYLINSMMRPLSMWLRHQRQIKNEDQLKSYAEEQ- 254

  Fly   472 PKAASPTNMNGNCKKDVTGVRNESQRQRHKSMGDLDGVKLNNLNGKGTVGTGAGSAASASATAAI 536
                         .|.:.|:..|.|....:.:       ||.|:......:...:.::....::.
Yeast   255 -------------LKLLLGITKEEQIDPGREL-------LNMLHTAVQANSNNNAVSNGQVPSSQ 299

  Fly   537 NSMNICNSNGKRNKQ--NAAAGSNQATPT---TIATPMTSNGAVVGGTV------SSKRQLF--- 587
            ...::...:|:.|:|  ..::.|:|..|:   :::.|..:|..|:..|:      .|..|||
Yeast   300 ELQHLKEQSGEHNQQKDQQSSFSSQQQPSIFPSLSEPFANNKNVIPPTMPMANVFMSNPQLFATM 364

  Fly   588 ----------------HSQSQN------------------------------------------- 593
                            :|.|.|
Yeast   365 NGQPFAPFPFMLPLTNNSNSANPIPTPVPPNFNAPPNPMAFGVPNMHNLSGPAVSQPFSLPPAPL 429

  Fly   594 --DAQQSASNEKQIVSSFDLIRKEK-QQQLKAAKAQKQQQQQQQRSRTKSQSDKQYNPQQPVKIL 655
              |:..|:|:..|::   |::..:| ...::::|..|.:..|:   .|...|.||.|..:...
Yeast   430 PRDSGYSSSSPGQLL---DILNSKKPDSNVQSSKKPKLKILQR---GTDLNSIKQNNNDETAH-- 486

  Fly   656 GQQQPTTGMDLIAMLSAAAAAQK----------TPNN----------EQQTQEKQQQQQRPRPAS 700
                 :....|:.:|....::||          .||:          |.......::.:..|...
Yeast   487 -----SNSQALLDLLKKPTSSQKIHASKPDTSFLPNDSVSGIQDAEYEDFESSSDEEVETARDER 546

  Fly   701 VSLNLGAGSATGATTSAPDAQYMHRLQRM-----ASGTNLRILKRAQS-------QQPQQHHQQQ 753
            .|||:..|     ....|..:...|.|:.     ||.|||.....:.|       ..|....:|.
Yeast   547 NSLNVDIG-----VNVMPSEKDSRRSQKEKPRNDASKTNLNASAESNSVEWGPGKSSPSTQSKQN 606

  Fly   754 LQLEQQQQQQQQLGI 768
            ..:..|.:.:|::.|
Yeast   607 SSVGMQNKYRQEIHI 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCP2	NP_001246776.1	DCP2	212..307	CDD:282833	33/93 (35%)
		Dcp2p	310..459	CDD:239644	48/149 (32%)
DCP2	NP_014281.1	DCP2	17..99	CDD:398619	30/80 (38%)
		Dcp2p	103..242	CDD:239644	48/138 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343723
Domainoid	1	1.000	81	1.000	Domainoid score	I2002
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002974
OrthoInspector	1	1.000	-	-		oto99848
orthoMCL	1	0.900	-	-		OOG6_102623
Panther	1	1.100	-	-	LDO	PTHR23114
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R299
SonicParanoid	1	1.000	-	-		X2325
TreeFam	1	0.960	-	-
	10	9.820