DRSC/TRiP Functional Genomics Resources

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Protein Alignment DCP2 and NUDT11

DIOPT Version :9

Sequence 1:NP_001246776.1 Gene:DCP2 / 39722 FlyBaseID:FBgn0036534 Length:792 Species:Drosophila melanogaster
Sequence 2:NP_060629.2 Gene:NUDT11 / 55190 HGNCID:18011 Length:164 Species:Homo sapiens


Alignment Length:132 Identity:36/132 - (27%)
Similarity:54/132 - (40%) Gaps:30/132 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   319 SEDHNHCLLVQSYFARNSWGFPKGKINENEDPAHCATREVYEETGFD-----ITDLIDANDYIEA 378
            ||..:..|||.|....:.|..|.|.:...|:|...|.||||||.|..     :..:.:.|.    
Human    27 SEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGVFEQNQ---- 87

  Fly   379 FINYQYTRLYVVRNIPM-----DTQFAPRTRNEIKCCDWFRI-DAL-------PVNKNDAISKAK 430
             .....|.:||:....:     |:....|.|      :||:: ||:       ||:. :.:.|.|
Human    88 -DRKHRTYVYVLTVTELLEDWEDSVSIGRKR------EWFKVEDAIKVLQCHKPVHA-EYLEKLK 144

  Fly   431 LG 432
            ||
Human   145 LG 146

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DCP2NP_001246776.1 DCP2 212..307 CDD:282833
Dcp2p 310..459 CDD:239644 36/132 (27%)
NUDT11NP_060629.2 Substrate binding. /evidence=ECO:0000250|UniProtKB:O95989 17..19
Nudix_Hydrolase_9 18..137 CDD:240024 32/120 (27%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:O95989 38..40 1/1 (100%)
Nudix box 50..71 10/20 (50%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:O95989 89..91 0/1 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 144..164 3/3 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0494
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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