Protein Alignment CkIIalpha-i1 and ZNF562

DIOPT Version :10

• Sequence 1: NP_524096.2
• Gene: CkIIalpha-i1 / 39721
• FlyBaseID: FBgn0015025
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001123503.1
• Gene: ZNF562 / 54811
• HGNCID: 25950
• Length: 426
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 90/455 - (19%)
• Similarity: 140/455 - (30%)
• Gaps: 161/455 - (35%)

  Fly    77 FHRRPIEIDDSTAFQIKLEVTSNKEEVETEKNDEENSFDQHIAEPVKE-----DPLEKNEHMEIV 136
            |.|.||     ..|:.|.::.:..|:..:....:..:||....|...|     |..:|..:.:::
Human    11 FPREPI-----CPFEEKTKIGTMVEDHRSNSYQDSVTFDDVAVEFTPEEWALLDTTQKYLYRDVM 70

  Fly   137 VEESLKTASVDFFSVGLS-------------RDGLAVTKFFKDKTQATR-----MLCTCCGHVLE 183
            :|..:..||||||....|             :.|....:.|......||     .||..||.|..
Human    71 LENYMNLASVDFFFCLTSEWEIQPRTKRSSLQQGFLKNQIFTGIQMQTRSYSGWKLCENCGEVFS 135

  Fly   184 ----ILTHIRMH--------SCKPRP-----------------NPV------------------- 200
                :.||:|..        :|..:.                 ||.
Human   136 EQFCLKTHMRAQNGGNTFEGNCYGKDSISVHKEASIGQELSKFNPCGKVFTLTPGLAVHLEILNG 200

  Fly   201 ---YYCRDCGSEFHKLHELHEHM------------------KTMKHNKTMC-----GAKDLEFLC 239
               |.|::||..|.....|..||                  .|..|.| .|     |.|..:  .
Human   201 RQPYKCKECGKGFKYFASLDNHMGIHIGEKLCEFQECERAITTSSHLK-QCVAVHTGKKSEK--T 262

  Fly   240 LRCNQIFPRYFDVIRHENSVHNVSDFICVECNMSFANQGSYRRHTRSHK-VK----------FTQ 293
            ..|.:.|..:..:..|..:......|.|.||..||.|..|:..|.:.|. :|          ||:
Human   263 KNCGKSFTNFSQLSAHAKTHKGEKSFECKECGRSFRNSSSFNVHIQIHTGIKPHKCTECGKAFTR 327

  Fly   294 Q-------------RFYECPYKDCTSSYRVWARLMSHMSSHGLFSGFKSKVPSTQQERRLLEGKF 345
            .             :.|||  |:|..::..:..|..|:.:|   :|.|   |...:|......:.
Human   328 STHLTQHVRTHTGIKPYEC--KECGQAFTQYTGLAIHIRNH---TGEK---PYQCKECGKAFNRS 384

  Fly   346 MTLDPMKRVEPDRRKLPYRKKSFYAKADFPESPTKCTNGGE-FISLPKKISLQKGKYINLSDNSR 409
            .||...:|:...                  |.|.:|...|: ||:     |..:.|::......|
Human   385 STLTQHRRIHTG------------------EKPYECVECGKTFIT-----SSHRSKHLKTHSGER 426

  Fly   410  409
            Human   427  426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIIalpha-i1	NP_524096.2	C2H2 Zn finger	239..259	CDD:275368	3/19 (16%)
		C2H2 Zn finger	267..287	CDD:275368	8/19 (42%)
		C2H2 Zn finger	299..321	CDD:275368	5/21 (24%)
ZNF562	NP_001123503.1	KRAB	40..81	CDD:460171	9/40 (23%)
		COG5048	<117..308	CDD:227381	39/193 (20%)
		C2H2 Zn finger	181..198	CDD:275370	0/16 (0%)
		C2H2 Zn finger	206..226	CDD:275368	7/19 (37%)
		COG5048	<258..420	CDD:227381	40/194 (21%)
		C2H2 Zn finger	263..282	CDD:275368	3/18 (17%)
		C2H2 Zn finger	290..310	CDD:275368	8/19 (42%)
		C2H2 Zn finger	318..338	CDD:275368	2/19 (11%)
		C2H2 Zn finger	346..366	CDD:275368	5/21 (24%)
		C2H2 Zn finger	374..394	CDD:275368	4/19 (21%)
		C2H2 Zn finger	402..422	CDD:275368	6/24 (25%)