Protein Alignment CkIIalpha-i1 and ZNF679

DIOPT Version :10

• Sequence 1: NP_524096.2
• Gene: CkIIalpha-i1 / 39721
• FlyBaseID: FBgn0015025
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_699194.2
• Gene: ZNF679 / 168417
• HGNCID: 28650
• Length: 411
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 84/427 - (19%)
• Similarity: 137/427 - (32%)
• Gaps: 123/427 - (28%)

  Fly    35 LFDWYKIDAA-------ILGENY--------CICEP----CFGETLRISESLEKWGTAQDEFHRR 80
            |.:|..:|.|       ::.|||        .:.:|    |      :.::.|.|...::|...:
Human    27 LEEWQCLDHAQQNLYRDVMLENYRNLVSLGIAVSKPDLITC------LEQNKEPWNIKRNEMVTK 85

  Fly    81 ------------PIEIDDSTAFQ--------------IKLEVTSNKEEVETEKN--DEENS---- 113
                        |.|:....:.|              ::::...:..|.|.:|.  :|.|.
Human    86 HPVMCSHFTQDLPPELGIKDSLQKVIPRRYGKSGHDNLQVKTCKSMGECEVQKGGCNEVNQCLST 150

  Fly   114 -----FDQHIAEPVKEDPLEKNEHMEIVVEESLKTASVDFFSVGLSRDGLAVTKFFKDK---TQA 170
                 |..|....|.......|.|      ::..|....|......:....|::..:.:   |:.
Human   151 TQNKIFQTHKCVKVFGKFSNSNRH------KTRHTGKKHFKCKKYGKSFCMVSQLHQHQIIHTRE 209

  Fly   171 TRMLCTCCGHVLE----ILTHIRMHSC-KPRPNPVYYCRDCGSEFHKLHELHEHMKTMKHNKTMC 230
            ....|..||....    :..|.|:|:. ||     |.|.:||..|.....|      .||.:...
Human   210 NSYQCEECGKPFNCSSTLSKHKRIHTGEKP-----YRCEECGKAFTWSSTL------TKHRRIHT 263

  Fly   231 GAKDLEFLCLRCNQIFPRYFDVIRHENSVHNVSDFICVECNMSFANQGSYRRHTRSHKVKFTQQR 295
            |.|  .:.|..|.|.|.|...:..|:........:.|.||..:|:...|...|.|.|    |.::
Human   264 GEK--PYTCEECGQAFSRSSTLANHKRIHTGEKPYTCEECGKAFSLSSSLTYHKRIH----TGEK 322

  Fly   296 FYECPYKDCTSSYRVWARLMSHMSSHGLFSGFKSKVPSTQQERRLLEGKFM----TLDPMKRVEP 356
            .|.|  ::|..::...:.|..|...|.....:|.|..          ||..    ||:..||:..
Human   323 PYTC--EECGKAFNCSSTLKKHKIIHTGEKPYKCKEC----------GKAFAFSSTLNTHKRIHT 375

  Fly   357 DRRKLPYR----KKSF--------YAKADFPESPTKC 381
            ...  ||:    .|:|        :......|.|.||
Human   376 GEE--PYKCEECDKAFKWSSSLANHKSMHTGEKPYKC 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIIalpha-i1	NP_524096.2	C2H2 Zn finger	239..259	CDD:275368	6/19 (32%)
		C2H2 Zn finger	267..287	CDD:275368	7/19 (37%)
		C2H2 Zn finger	299..321	CDD:275368	4/21 (19%)
ZNF679	NP_699194.2	KRAB	16..76	CDD:214630	10/54 (19%)
		C2H2 Zn finger	159..178	CDD:275368	4/24 (17%)
		C2H2 Zn finger	186..206	CDD:275368	1/19 (5%)
		C2H2 Zn finger	214..234	CDD:275368	5/19 (26%)
		COG5048	<238..401	CDD:227381	45/193 (23%)
		C2H2 Zn finger	242..262	CDD:275368	7/25 (28%)
		C2H2 Zn finger	270..290	CDD:275368	6/19 (32%)
		C2H2 Zn finger	298..318	CDD:275368	7/19 (37%)
		C2H2 Zn finger	326..346	CDD:275368	4/21 (19%)
		C2H2 Zn finger	354..374	CDD:275368	7/29 (24%)
		C2H2 Zn finger	382..402	CDD:275368	2/19 (11%)