Protein Alignment CkIIalpha-i1 and ZNF114

DIOPT Version :10

• Sequence 1: NP_524096.2
• Gene: CkIIalpha-i1 / 39721
• FlyBaseID: FBgn0015025
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001318027.1
• Gene: ZNF114 / 163071
• HGNCID: 12894
• Length: 463
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 61/272 - (22%)
• Similarity: 97/272 - (35%)
• Gaps: 61/272 - (22%)

  Fly    42 DAAILGENYCICEPCFGETLRISESLEKWGTAQDEFHRRPIEIDDST----------AFQ----I 92
            |..:||.| ....|| |....:..|  .|..:|:..|....|||...          ||:    :
Human   222 DDGVLGWN-IQWVPC-GRKTELKSS--TWTGSQNTVHHIRDEIDTGANRHQRNPFGKAFREDGSL 282

  Fly    93 KLEVTSNKEEV----ETEKNDEENSFDQHIAEPVKEDPLEKNEHMEI-VVEESLKTASVDFFSVG 152
            :...|..:|::    :.|.....||.  |..:            |:: ..|.:.|.......|..
Human   283 RAHNTHGREKMYDFTQCENTSRNNSI--HAMQ------------MQLYTAETNKKDCQTGATSAN 333

  Fly   153 LSRDGLAVTKFFKDKTQATRMLCTCCGHVL----EILTHIRMHSC-KPRPNPVYYCRDCGSEF-H 211
            ....|...:....:||..    |..||...    .::.|:::|:. ||     |.|..||..| :
Human   334 APNSGSHKSHCTGEKTHK----CPECGRAFFYQSFLMRHMKIHTGEKP-----YECGKCGKAFRY 389

  Fly   212 KLHELHEHMKTMKHNKTMCGAKDLEFLCLRCNQIFPRYFDVIRHENSVHNVSDFICVECNMSFAN 276
            .|| |::|::  ||   :...|..|  |..|.::. |......|..|......:.|..|...||.
Human   390 SLH-LNKHLR--KH---VVQKKPYE--CEECGKVI-RESSKYTHIRSHTGEKPYKCKTCGKDFAK 445

  Fly   277 QGSYRRHTRSHK 288
            ....::|.::||
Human   446 SSGLKKHLKTHK 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIIalpha-i1	NP_524096.2	C2H2 Zn finger	239..259	CDD:275368	4/19 (21%)
		C2H2 Zn finger	267..287	CDD:275368	5/19 (26%)
		C2H2 Zn finger	299..321	CDD:275368
ZNF114	NP_001318027.1	KRAB	51..92	CDD:460171
		zf-C2H2	350..372	CDD:395048	4/25 (16%)
		C2H2 Zn finger	352..372	CDD:275368	4/19 (21%)
		zf-H2C2_2	365..389	CDD:463886	9/28 (32%)
		C2H2 Zn finger	380..428	CDD:275368	16/56 (29%)
		zf-H2C2_2	424..445	CDD:463886	5/20 (25%)
		C2H2 Zn finger	436..456	CDD:275368	5/19 (26%)