DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant8 and Galnt15

DIOPT Version :9

Sequence 1:	NP_648800.1	Gene:	Pgant8 / 39715	FlyBaseID:	FBgn0036529	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_006519762.1	Gene:	Galnt15 / 78754	MGIID:	1926004	Length:	652	Species:	Mus musculus

Alignment Length:	664	Identity:	189/664 - (28%)
Similarity:	307/664 - (46%)	Gaps:	135/664 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLLLMAIGSIIYYLYTL---------KLEGERDESATSTTSRLERDIRDLQA-VFESEVIPD--- 66
            |||.:.:|.::..:..|         .:..:..:.:..|..||  |..|.|. |.|:|...|
Mouse    17 LLLFLTLGCVLMMVILLHPPPPTLHQAVTAQASKHSPDTGYRL--DFGDSQEWVLEAETEGDEYS 79

  Fly    67 ----------------LGALGRP------ARG--------------NWTEEQLEAIAKSQRE--- 92
                            |.|:..|      ::|              .|.||.||...:::.:
Mouse    80 LLDGLPSFISLQEDQLLVAVASPRARRSQSQGRRQGSYQFIKHRSRRWDEEALEKDWRTEEDGEE 144

  Fly    93 ------------TGYNAWLSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLL 145
                        .|.|..||.|:...|.|.::||..|.: ::|...||:.||::.:|:|....||
Mouse   145 SEEVLTPLGPDSDGLNKPLSARLPLRRVLPEVRHPLCLQ-QHPTSGLPTASVILCFHDEAWPTLL 208

  Fly   146 RTLSSLRSRTPIQLLREVILVDDGSTQ--ADEKLNDFI-KIKFLNMVQHRRITTQVGLMHARVVG 207
            ||:.|:....|..||:|:|||||.|.|  ....|:::: :::.:.:::..|   ::|.:.||::|
Mouse   209 RTVHSILDTAPRALLQEIILVDDLSQQELLKSALSEYVARLEAVKLLRSNR---RLGTIGARMLG 270

  Fly   208 AELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNWE 272
            |..|..|||||:|:|.|...||||||::.|.:|.....:|:||.||:....|...|..||..:|:
Mouse   271 ATRATGDVLVFMDAHCECHPGWLEPLLSRIADDRSRVVSPVIDVIDWKTLQYSASKLHRGTLDWK 335

  Fly   273 FNYIQLPLLKEEAVAMP---APHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLW 334
            .::...||.::|..|:|   :|.::|::...:.|:.|.:|...|.||..|.:..:|..|:|.|.|
Mouse   336 LDFRWKPLGEQEQKALPSPISPVRSPVVPREVVAVDRHYFQNTGAYDPLLSLGDSENLEMSFKAW 400

  Fly   335 LCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNS--EKKLISRNYRRVAEIWLDEYKDKLFANMP 397
            ||||.:..:|||||||::|         ::|.:|  :.::..:|...:||.||..:|:..:.::|
Mouse   401 LCGGSVEILPCSRVGHIYR---------SQDASSRPDPEVALKNKIIIAETWLSSFKETFYRHIP 456

  Fly   398 H---LTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYA---SGVLQSISSP 456
            .   |:.:...:..|:..|:.||.|:.|.|||       .|:||.|.|:::.   ||.|.: :..
Mouse   457 EAFTLSKVAKPDCTERLKLQRRLGCRTFHWFL-------ANVYPELYPSDHRPRFSGKLHN-TGF 513

  Fly   457 KLCLDRKDPSH--GQP-KLAPCSSDH-----------VFPSPEQYWSLTNHRELRSG---FYCLE 504
            .||.|.:....  |.| .|||||::.           ..|| .|....|..:|:..|   ..|.:
Mouse   514 GLCADCQADGDILGCPMTLAPCSNNRQQQGTLLAMLTATPS-AQNLEHTGRKEILFGGPQRLCFD 577

  Fly   505 VRNHGVNVHIYQCHGQS---GNQFWSF--DSKTHQVISGQQQNFRHCLEA--QPELNAVTSSVCD 562
            ||  |..|.:..|..:.   ..|.|.|  |.....|:||:      |:||  ||....:....||
Mouse   578 VR--GGRVILQNCTEEGPAIHQQHWDFQEDGMIIHVLSGK------CMEAGVQPSNKDLYLRQCD 634

  Fly   563 PKNHKQQWKFGYLN 576
            .|. .|.|:|..::
Mouse   635 GKT-SQLWRFDQIH 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	104/309 (34%)
		pp-GalNAc-T	131..430	CDD:133004	104/309 (34%)
		Ricin_B_lectin	446..570	CDD:279046	41/150 (27%)
		RICIN	448..572	CDD:238092	41/147 (28%)
Galnt15	XP_006519762.1	pp-GalNAc-T	194..492	CDD:133004	105/316 (33%)
Galnt15	XP_006519762.1	Ricin_B_lectin	504..641	CDD:366226	41/147 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842543
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740