Protein Alignment Pgant8 and Galnt15

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_006519762.1
• Gene: Galnt15 / 78754
• MGIID: 1926004
• Length: 652
• Species: Mus musculus
• Alignment Length: 664
• Identity: 189/664 - (28%)
• Similarity: 307/664 - (46%)
• Gaps: 135/664 - (20%)

  Fly    15 LLLLMAIGSIIYYLYTL---------KLEGERDESATSTTSRLERDIRDLQA-VFESEVIPD--- 66
            |||.:.:|.::..:..|         .:..:..:.:..|..||  |..|.|. |.|:|...|
Mouse    17 LLLFLTLGCVLMMVILLHPPPPTLHQAVTAQASKHSPDTGYRL--DFGDSQEWVLEAETEGDEYS 79

  Fly    67 ----------------LGALGRP------ARG--------------NWTEEQLEAIAKSQRE--- 92
                            |.|:..|      ::|              .|.||.||...:::.:
Mouse    80 LLDGLPSFISLQEDQLLVAVASPRARRSQSQGRRQGSYQFIKHRSRRWDEEALEKDWRTEEDGEE 144

  Fly    93 ------------TGYNAWLSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLL 145
                        .|.|..||.|:...|.|.::||..|.: ::|...||:.||::.:|:|....||
Mouse   145 SEEVLTPLGPDSDGLNKPLSARLPLRRVLPEVRHPLCLQ-QHPTSGLPTASVILCFHDEAWPTLL 208

  Fly   146 RTLSSLRSRTPIQLLREVILVDDGSTQ--ADEKLNDFI-KIKFLNMVQHRRITTQVGLMHARVVG 207
            ||:.|:....|..||:|:|||||.|.|  ....|:::: :::.:.:::..|   ::|.:.||::|
Mouse   209 RTVHSILDTAPRALLQEIILVDDLSQQELLKSALSEYVARLEAVKLLRSNR---RLGTIGARMLG 270

  Fly   208 AELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNWE 272
            |..|..|||||:|:|.|...||||||::.|.:|.....:|:||.||:....|...|..||..:|:
Mouse   271 ATRATGDVLVFMDAHCECHPGWLEPLLSRIADDRSRVVSPVIDVIDWKTLQYSASKLHRGTLDWK 335

  Fly   273 FNYIQLPLLKEEAVAMP---APHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLW 334
            .::...||.::|..|:|   :|.::|::...:.|:.|.:|...|.||..|.:..:|..|:|.|.|
Mouse   336 LDFRWKPLGEQEQKALPSPISPVRSPVVPREVVAVDRHYFQNTGAYDPLLSLGDSENLEMSFKAW 400

  Fly   335 LCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNS--EKKLISRNYRRVAEIWLDEYKDKLFANMP 397
            ||||.:..:|||||||::|         ::|.:|  :.::..:|...:||.||..:|:..:.::|
Mouse   401 LCGGSVEILPCSRVGHIYR---------SQDASSRPDPEVALKNKIIIAETWLSSFKETFYRHIP 456

  Fly   398 H---LTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYA---SGVLQSISSP 456
            .   |:.:...:..|:..|:.||.|:.|.|||       .|:||.|.|:::.   ||.|.: :..
Mouse   457 EAFTLSKVAKPDCTERLKLQRRLGCRTFHWFL-------ANVYPELYPSDHRPRFSGKLHN-TGF 513

  Fly   457 KLCLDRKDPSH--GQP-KLAPCSSDH-----------VFPSPEQYWSLTNHRELRSG---FYCLE 504
            .||.|.:....  |.| .|||||::.           ..|| .|....|..:|:..|   ..|.:
Mouse   514 GLCADCQADGDILGCPMTLAPCSNNRQQQGTLLAMLTATPS-AQNLEHTGRKEILFGGPQRLCFD 577

  Fly   505 VRNHGVNVHIYQCHGQS---GNQFWSF--DSKTHQVISGQQQNFRHCLEA--QPELNAVTSSVCD 562
            ||  |..|.:..|..:.   ..|.|.|  |.....|:||:      |:||  ||....:....||
Mouse   578 VR--GGRVILQNCTEEGPAIHQQHWDFQEDGMIIHVLSGK------CMEAGVQPSNKDLYLRQCD 634

  Fly   563 PKNHKQQWKFGYLN 576
            .|. .|.|:|..::
Mouse   635 GKT-SQLWRFDQIH 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	104/309 (34%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	42/154 (27%)
Galnt15	XP_006519762.1	pp-GalNAc-T	194..492	CDD:133004	105/316 (33%)
		beta-trefoil_Ricin_GALNT15	501..642	CDD:467320	41/151 (27%)