Protein Alignment Pgant8 and GALNT17

DIOPT Version :9

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_071924.1
• Gene: GALNT17 / 64409
• HGNCID: 16347
• Length: 598
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 181/607 - (29%)
• Similarity: 286/607 - (47%)
• Gaps: 122/607 - (20%)

  Fly    11 KVLPLLLLMAIGSIIYYL--------------YTLKLEGERDESATSTTSRLERDIRDLQAVFES 61
            |||.:|.|:|:...:.:|              :.::...|....:..:.|.::..:....::.|.
Human     8 KVLLVLNLIAVAGFVLFLAKCRPIAVRSGDAFHEIRPRAEVANLSAHSASPIQDAVLKRLSLLED 72

  Fly    62 EVIPDLGAL----------------GRPARGNWTEEQLEAIAKSQRET-GYNAWLSKRISPERSL 109
            .|...|..|                |.||..:..||:.   ||...|. |||::||::||.:||:
Human    73 IVYRQLNGLSKSLGLIEGYGGRGKGGLPATLSPAEEEK---AKGPHEKYGYNSYLSEKISLDRSI 134

  Fly   110 YDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQAD 174
            .|.|...||:|||..: ||.:|::..:.||..||:||::.|..:.||..||:|:|||||.|.:.:
Human   135 PDYRPTKCKELKYSKD-LPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEE 198

  Fly   175 EK--LNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPI 237
            .|  |.:::..::..:|:..|...:.||:.||:.|.::|...|..|.|:|||.|.||.||:::.|
Human   199 LKVPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWAEPVLSRI 263

  Fly   238 LEDNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNWEF--NYIQLPLLKEEAVAMPAPHKNPIMNGG 300
            .|:.:....|.||.|..|||..:|.:.|...::||.  .||..|....:|.....|.:.|.|.|.
Human   264 QENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGC 328

  Fly   301 LFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDG---NFQIRYT 362
            .|.:.|::|.|:|..|.|:.::|.|..||.:|:|||||.:..:|||||.|:.|..   |..|.:.
Human   329 SFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFY 393

  Fly   363 NKDKNSEKKLISRNYRRVAEIWLDEYKDKLFA--NMP-HLTVIPVGNLAEQRDLKNRLHCKPFKW 424
            .|          ||..||||:|:|:||..::.  |:| ....|.:|:::|:|.|:..|.||.|:|
Human   394 TK----------RNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRKSLKCKNFQW 448

  Fly   425 FLDNLATDFLNLYPILDPAEY----ASGVLQSISSPKLCLDRKD---------PSHG-------- 468
            :||       ::||  :...|    |.|.|::..:..:|||:..         |.||
Human   449 YLD-------HVYP--EMRRYNNTVAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARY 504

  Fly   469 ------------------------------QPKLAPCSSDHVFPSPEQYWS-LTNHRELRSGF-Y 501
                                          .|:|..|  |.|..|..:.|: :.|...:..|. .
Human   505 TKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDC--DKVKSSLYKRWNFIQNGAIMNKGTGR 567

  Fly   502 CLEVRNH---GVNVHIYQCHGQ 520
            ||||.|.   |:::.:..|.||
Human   568 CLEVENRGLAGIDLILRSCTGQ 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	111/308 (36%)
		pp-GalNAc-T	131..430	CDD:133004	112/308 (36%)
		Ricin_B_lectin	446..570	CDD:279046	27/127 (21%)
		RICIN	448..572	CDD:238092	26/125 (21%)
GALNT17	NP_071924.1	Catalytic subdomain A	151..262		42/110 (38%)
		pp-GalNAc-T	155..454	CDD:133004	112/315 (36%)
		Catalytic subdomain B	319..381		27/61 (44%)
		RICIN	467..593	CDD:238092	26/125 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740