Protein Alignment Pgant8 and GALNT11

DIOPT Version :9

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001358393.1
• Gene: GALNT11 / 63917
• HGNCID: 19875
• Length: 667
• Species: Homo sapiens
• Alignment Length: 519
• Identity: 183/519 - (35%)
• Similarity: 270/519 - (52%)
• Gaps: 62/519 - (11%)

  Fly    53 RDLQAVFESEVIPDL--GALGRPARG------------NWTEEQLEAIAKSQRETGY-----NAW 98
            |.|:..|::..|.|:  ..:..|..|            |..:::|       |:.||     |..
Human    65 RVLEPQFKANKIDDVIDSRVEDPEEGHLKFSSELGMIFNERDQEL-------RDLGYQKHAFNML 122

  Fly    99 LSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREV 163
            :|.|:...|.:.|.|:.:||:..||.: ||:.||||.::||..|.||||:.|:..|||..||.|:
Human   123 ISDRLGYHRDVPDTRNAACKEKFYPPD-LPAASVVICFYNEAFSALLRTVHSVIDRTPAHLLHEI 186

  Fly   164 ILVDDGSTQADEK--LNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVT 226
            |||||.|...|.|  |:::::......::..|.|.:.||:..|::||..|..:||||||||.||.
Human   187 ILVDDDSDFDDLKGELDEYVQKYLPGKIKVIRNTKREGLIRGRMIGAAHATGEVLVFLDSHCEVN 251

  Fly   227 KGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNW--EFNYIQLPLLK-EEAVAM 288
            ..||:||:|.|.||..|...|:||.|..|..||......||.|||  .|.:..:||.: ..|...
Human   252 VMWLQPLLAAIREDRHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPLSELGRAEGA 316

  Fly   289 PAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFR 353
            .||.|:|.|.|||||:.|::|.|||.||.|:.|||.|..|:|.::|:|||::..:|||||||:||
Human   317 TAPIKSPTMAGGLFAMNRQYFHELGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFR 381

  Fly   354 DGNFQIRYTNKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLH 418
            .   :..|.:.:   .:..::.|..|:|.:||||||::.|:..|.|.....||::|:.:|:.:|.
Human   382 K---RRPYGSPE---GQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSYGNISERVELRKKLG 440

  Fly   419 CKPFKWFLDNLATD--------------FLNLYPILDPAEYASGVLQSISSPKLCLDRKDPSH-- 467
            ||.|||:|||:..:              |:|..| ..|.....|.|..:.:.|..:.:..||.
Human   441 CKSFKWYLDNVYPEMQISGSHAKPQQPIFVNRGP-KRPKVLQRGRLYHLQTNKCLVAQGRPSQKG 504

  Fly   468 GQPKLAPCSSDHVFPSPEQYWSLTNHREL-RSGFYCLEVRNHGVN--VHIYQCHGQSGNQFWSF 528
            |...|..|.    :..|.|.|......|| .:...||::.....:  ..:.:|||..|:|.|:|
Human   505 GLVVLKACD----YSDPNQIWIYNEEHELVLNSLLCLDMSETRSSDPPRLMKCHGSGGSQQWTF 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	131/303 (43%)
		pp-GalNAc-T	131..430	CDD:133004	133/303 (44%)
		Ricin_B_lectin	446..570	CDD:279046	22/88 (25%)
		RICIN	448..572	CDD:238092	22/86 (26%)
GALNT11	NP_001358393.1	Catalytic subdomain A	150..261		51/110 (46%)
		pp-GalNAc-T	154..452	CDD:133004	133/303 (44%)
		Catalytic subdomain B	319..381		34/61 (56%)
		Ricin_B_lectin	483..>564	CDD:366226	21/84 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152530
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740