Protein Alignment Pgant8 and galnt8a.2

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_073799092.1
• Gene: galnt8a.2 / 568500
• ZFINID: ZDB-GENE-131122-40
• Length: 609
• Species: Danio rerio
• Alignment Length: 640
• Identity: 190/640 - (29%)
• Similarity: 299/640 - (46%)
• Gaps: 117/640 - (18%)

  Fly    17 LLMAIGSIIYYLYTLK-LEGERDESAT----------STTSRLERDIRDL----------QAVFE 60
            :|..||.|:|.:..:. :..||:..:|          ....|:|.::.::          :||.:
Zfish     9 VLFIIGIIVYSVVNVSFIRPERNNDSTLQKPEEIELFQRLKRIEDEVHEIAINIKNQNVKEAVVK 73

  Fly    61 SEV--------IPDLGALGRPARGNWTEEQLEAIAKSQRETGYNAWLSKRISPERSLYDMRHRSC 117
            .::        :....||.:......|||:.....|..:|.|||.:||.|:...|::.|.|...|
Zfish    74 QKITKKTEVKKLYPKSALFKTWGAELTEEEQMEAEKLFQEFGYNVFLSNRLPLNRTIPDTRDPRC 138

  Fly   118 KKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQADEKLN---- 178
            ....||.: ||::||::.|.||..||:.|.:.|:..:||..||:|::||||.|:..|.||.
Zfish   139 SLKIYPKD-LPTISVILIYLNEALSVIKRAVQSIIDKTPAHLLKEIVLVDDNSSNEDLKLPLDKY 202

  Fly   179 -DFI---KIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILE 239
             |.|   |...:..|:|::   |:||..||:.|.|.|...|:..||:|:||.|.|.|||:|.|..
Zfish   203 IDLINKGKPGLIKKVRHKK---QMGLAKARMSGWEAATGQVVAILDAHIEVHKEWAEPLLAQIKA 264

  Fly   240 DNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNWEFNYIQLPLLKEEAVAM--PA-PHKNPIMNGGL 301
            :..|..:|:.|.:.||.....:..|:...|:|.. :......:.|...:  |: |.|:|.:.|.|
Zfish   265 NRTTVLSPVFDKVLFDTLEVIKYNPAAHAFDWSL-WCMYERFRPEWYKLKDPSEPGKSPSVMGIL 328

  Fly   302 FAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDK 366
            .| .||:..|:|..|:|:.|:|.|..||.:::|||||.:..||||::.|:.|        .:|..
Zfish   329 VA-DREFLGEIGVLDEGMTIYGGENVELGIRVWLCGGSVEVVPCSKIAHVER--------AHKPY 384

  Fly   367 NSE-KKLISRNYRRVAEIWLDEYKD--KLFANMP---HLTVIPVGNLAEQRDLKNRLHCKPFKWF 425
            :.: .||:.||..||||||:||||.  .:..|:|   |  .|.:||:.|::.|:.:|.||||||:
Zfish   385 SPDLSKLMIRNALRVAEIWMDEYKSNVNIAWNLPLKDH--GIDIGNVTERKQLREKLKCKPFKWY 447

  Fly   426 LDNLATDFLNLYPILDPAE--YASGVLQSISSPKLCLDRKDPSHGQPKLAPCSSDHVFPSPEQYW 488
            |:       |:||:||..:  ...|||::......|:|:.......|.|..|   |.:.....|:
Zfish   448 LE-------NVYPLLDRWDDILGYGVLKNDILKTHCIDQGPVPGSVPVLFGC---HYYGPQRCYY 502

  Fly   489 SLTNH---RELRSGFY----CLEVRNHGVNVHIYQCHGQSGNQF---WSF-------DSKTHQVI 536
            ..|..   ..::|..|    ||.....|..|.:|.|.......|   |.|       :.||::.|
Zfish   503 KRTGEIYVGSIKSHTYNSNRCLTDPGSGSTVTLYNCKYAKEKGFSIYWDFTQGKEIRNKKTNRCI 567

  Fly   537 ---SGQQQNFRHCLEAQPELNAVTSSVCDPKNHKQQWKFGYLNSQRLQHFWDNVK 588
               .||...:...|:|           |.    .|:|        .:||.::.:|
Zfish   568 ELAQGQDTYYYLVLQA-----------CT----GQEW--------TIQHAFEELK 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	117/315 (37%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	32/147 (22%)
galnt8a.2	XP_073799092.1	None