Protein Alignment Pgant8 and galnt17

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_696189.5
• Gene: galnt17 / 567794
• ZFINID: ZDB-GENE-110419-5
• Length: 617
• Species: Danio rerio
• Alignment Length: 619
• Identity: 186/619 - (30%)
• Similarity: 286/619 - (46%)
• Gaps: 129/619 - (20%)

  Fly     5 IWRHKKKVLPLLLLMAIGSIIYY----LYTLK---------------LEGERDESATSTTSRLER 50
            :.|..|.:|.|.:....|.|.::    :.|.|               |.|...|::.:....|:|
Zfish    17 VMRRWKILLVLNVFTVAGFITFWGKCNVRTTKGVGQQMAVDSRGQTNLNGSVQETSITHDVLLKR 81

  Fly    51 -----DI--RDLQAVFES-EVIPDLGALGR---PARGNWTEEQLEAIAKSQRET-GYNAWLSKRI 103
                 |:  |.|..:.:| .:|...|..||   ||.....||:   .||..||. ||||:||.:|
Zfish    82 LGSLEDVVYRQLNGLSKSLGLIEGFGGRGRGGIPATLTPAEEK---EAKFLREKYGYNAFLSDKI 143

  Fly   104 SPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDD 168
            |.:|||.|.|...|||..:|.: ||.:|::..:.||..||:||::.|..:.||..||:|:|||||
Zfish   144 SLDRSLPDYRPSKCKKAFFPRD-LPQISIIFIFVNEALSVILRSVHSAVNHTPAHLLKEIILVDD 207

  Fly   169 GSTQADEK--LNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLE 231
            .|.....|  |.:::..::..:::..|...:.||:.||:.|.::|..:|..|.|:|||.|..|.|
Zfish   208 NSDDVQLKGPLEEYVNKRYPGLIKIVRNQKREGLIRARIEGWKVATGEVTGFFDAHVEFTPAWAE 272

  Fly   232 PLIAPILEDNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNWEF--NYIQLPLLKEEAVAMPAPHKN 294
            |:::.|.|:::....|.||.|..:.|...|.:.|...:|||.  .||..|....:.....||.:.
Zfish   273 PVLSRIKENHKRIILPSIDNIKDETFELERYENSGHGYNWELWCMYISPPKQWWDEGDTSAPIRT 337

  Fly   295 PIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQI 359
            |.|.|..|.:.||:|.:||..|.|:.::|.|..||.:::|||||.:..:|||||.|:.|
Zfish   338 PAMIGCSFVVNREYFGDLGLLDAGMDVYGGENIELGIRVWLCGGSMEVLPCSRVAHIAR------ 396

  Fly   360 RYTNKDKNSEKKL-ISRNYRRVAEIWLDEYKDKLFA--NMP---HLTVIPVGNLAEQRDLKNRLH 418
              |.|..:|.... ..||..||||:|:|:||..::.  |:|   |  .|..|:::|:..|:.||.
Zfish   397 --TKKPYHSNIAFHTRRNALRVAEVWMDQYKSNVYLAWNLPMKNH--GIDYGDVSERLALRKRLQ 457

  Fly   419 CKPFKWFLDNLATDFLNLYPILDPAEYAS----GVLQSISSPKLCLDR--KD-------PSHG-- 468
            ||.|.|:||       |:||  :...|.:    |.:::.:...||:|:  |:       |.||
Zfish   458 CKSFDWYLD-------NIYP--EMRRYNNTVFYGEIRNTNVTHLCVDQGIKENHTATLHPCHGWG 513

  Fly   469 ----------------------------------QPKLAPCSSDHVFPSPEQYWSLTNHREL--R 497
                                              .|:|..|  :.|....::.|....:..:  |
Zfish   514 PQLGRYTKEGYLFLGPLGSTGEDTRCVVDDKISSYPQLLNC--EKVSSVRQKTWHFAQNESIISR 576

  Fly   498 SGFYCLEVRNHGVNVHIY--------QCHGQSGN 523
            :...||||    |..::|        .|.||..|
Zfish   577 ATGRCLEV----VPANVYFGYALILRSCTGQKWN 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	110/308 (36%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	25/138 (18%)
galnt17	XP_696189.5	pp-GalNAc-T	170..469	CDD:133004	111/315 (35%)
		beta-trefoil_Ricin_GALNT8-like	477..609	CDD:467316	24/136 (18%)