Protein Alignment Pgant8 and galnt8b.1

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_021331085.2
• Gene: galnt8b.1 / 559373
• ZFINID: ZDB-GENE-041210-83
• Length: 629
• Species: Danio rerio
• Alignment Length: 679
• Identity: 196/679 - (28%)
• Similarity: 297/679 - (43%)
• Gaps: 167/679 - (24%)

  Fly    10 KKVLPLLLLMAIGSIIYYLYTLKLEGERDES------------ATSTTSRLERDIRDLQAVFES- 61
            |.:.|:|   ::..:..||.::|.|.:..|.            ::....:|::....|.||.||
Zfish     7 KSLFPVL---SVAVVFLYLSSVKWEIKTQEEKLQQVQQNLSLHSSLLLHKLDKLEAHLIAVEESR 68

  Fly    62 -----------EVIPDLGALGRPARGNWTEEQLEAIAKSQRET-------GYNAWLSKRISPERS 108
                       ::.||.....|     |:.|..|   ..||:.       ||||:||.|:..:|.
Zfish    69 LKVKSEKKPAKKLFPDSDLFKR-----WSVELSE---YEQRKAEDLFQKYGYNAFLSDRLPLDRE 125

  Fly   109 LYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQA 173
            |.|.|...|.:.:||.: ||:||||:.|.:|..||:.|.:.|:.:|||..||:|:|||||.||..
Zfish   126 LPDTRDHRCAEREYPPD-LPTVSVVLIYLDEALSVIQRAVYSIINRTPAHLLKEIILVDDHSTNE 189

  Fly   174 DEKLNDFIKIKFLN--------MVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWL 230
            |.:....:.|..:|        ||.|   ..|.||..||:.|.:.|..||:..||:|:||...|.
Zfish   190 DLQTQLHVYISSINEKHPGLVKMVTH---AEQKGLSQARISGWKAASGDVVAILDAHIEVHVKWA 251

  Fly   231 EPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNWEF--NYIQLPLLKEEAVAMPAPHK 293
            |||:|.|..|.....:|:.|.|::|:....:...|...|:|..  .|:..|...........|.|
Zfish   252 EPLLARIQADRTLVLSPVFDKINYDDLEVTKYFASAHGFDWALWCMYVTFPKKWYNRNDPSLPGK 316

  Fly   294 NP-IMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLK------------------------- 332
            :| :|  |:..:.|.:|.|:|..|:|::::|.|..||.::
Zfish   317 SPSVM--GILVVDRLFFGEIGTLDEGMQVYGGENVELGIRVIHHHTEAFFILLYLHVEQWCCCSL 379

  Fly   333 ---------LWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNSE-KKLISRNYRRVAEIWLDE 387
                     :|||||.|..||||::.|:.|        .:|....: ..::.||..||||:|:||
Zfish   380 LTFGCVLAQVWLCGGSIEVVPCSKIAHIER--------AHKPYMPDLSNVMKRNALRVAEVWMDE 436

  Fly   388 YKDKLFA--NMP---HLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYAS 447
            ||..::.  .:|   |  .|.:|:|:|::.|:.|::||||||:|:|:.|:   |.|:.|...|
Zfish   437 YKKNVYMAWGLPLENH--GIDIGDLSERKKLRERMNCKPFKWYLENVYTE---LNPMDDLLGY-- 494

  Fly   448 GVLQSISSPKLCLDRKDPSHGQPKLAPCSSDHVFPSPEQYWSLTNHRELRSGFYCLEVRNHGVNV 512
            |.|.:.....||||:.......|.|.||   |...|  |.:..|...|:..|  .|:...|..|
Zfish   495 GALINDLQTGLCLDKGPSEENTPILYPC---HFLTS--QVFFYTTSGEILVG--PLQPLLHSRN- 551

  Fly   513 HIYQCHGQSG-----------------NQFWSFDSKTHQVISGQQQNFRHCLEAQPELNAVTSSV 560
               :|....|                 :.:|.|  |..|.|  |.::.:.|||..      |...
Zfish   552 ---RCLADPGSGRFPEFSWCSDTEKPKHMYWDF--KQGQAI--QNRDTKRCLEIS------TKQT 603

  Fly   561 CDPKNH-------KQQWKFGYLNSQRLQH 582
            .|.||:       .|.|        |:||
Zfish   604 GDYKNNVFIQECRNQHW--------RIQH 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	113/349 (32%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	37/151 (25%)
galnt8b.1	XP_021331085.2	None