Protein Alignment Pgant8 and GALNT10

DIOPT Version :9

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_938080.1
• Gene: GALNT10 / 55568
• HGNCID: 19873
• Length: 603
• Species: Homo sapiens
• Alignment Length: 554
• Identity: 198/554 - (35%)
• Similarity: 309/554 - (55%)
• Gaps: 45/554 - (8%)

  Fly    50 RDIRDLQAVFESEVIPDLGALGRPARGNWTEEQLEAIAKSQRETGYNAWLSKRISPERSLYDMRH 114
            :|..|.:|:.........|..|||    :.....|.:.::.||.|:|.::|.:||..|||.|:||
Human    72 KDWHDKEAIRRDAQRVGNGEQGRP----YPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIRH 132

  Fly   115 RSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQADEK--L 177
            .:|...:| :|.||:.|::|.:|||..|.||||:.|:.:|:|.:|:.|::||||.|.:...|  |
Human   133 PNCNSKRY-LETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPL 196

  Fly   178 NDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNR 242
            .|::.:  ...|:..|...:.||:..|::||.:|..||:.|||||.|....||.||:..|..:.:
Human   197 EDYMAL--FPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRK 259

  Fly   243 TCTTPIIDTIDFDNFAY--RRGKPSRGFFNWEFNYIQLPLLKEEAVAMPA-PHKNPIMNGGLFAI 304
            |...|:||.||.|:|.|  :.|...||.|:||..|.::|:..|...|.|: |.::|:|.|||||:
Human   260 TIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAV 324

  Fly   305 GREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNSE 369
            .|:||.||||||.||:|||.||:|:|.|:|:|||::.::|||||||::|.   .:.|    |...
Human   325 DRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRK---YVPY----KVPA 382

  Fly   370 KKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFL 434
            ...::||.:||||:|:|||.:.::...|....:..|::|.|:.|::.|:||.||||:..:|.|..
Human   383 GVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLP 447

  Fly   435 NLYPILDPAEYASGVLQSISSPKLCLDRKDPSHGQP-KLAPCSSDHVFPSPEQYW------SLTN 492
            ..||.::|...|.|.::::.: .||.|.|..:.|.| :|..|    |....|..|      :.|.
Human   448 KFYPPVEPPAAAWGEIRNVGT-GLCADTKHGALGSPLRLEGC----VRGRGEAAWNNMQVFTFTW 507

  Fly   493 HRELRSG------FYCLEVRNHGVNVHIYQCHGQSGNQFWSF--DSKTHQVISGQQQNFRHCLEA 549
            ..::|.|      .:|.:..:|...|.:|.||...|||.|.:  |...:..:||.      |::.
Human   508 REDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGS------CMDC 566

  Fly   550 QPELNAVTSSVCDPKNHKQQWKFGYLNSQRLQHF 583
            ....:.:..:.|:|.:..|||.|.:.||..|:.|
Human   567 SESDHRIFMNTCNPSSLTQQWLFEHTNSTVLEKF 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	128/303 (42%)
		pp-GalNAc-T	131..430	CDD:133004	127/303 (42%)
		Ricin_B_lectin	446..570	CDD:279046	33/138 (24%)
		RICIN	448..572	CDD:238092	34/138 (25%)
GALNT10	NP_938080.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..59
		Catalytic subdomain A	144..253		45/110 (41%)
		GT2	145..449	CDD:224137	130/312 (42%)
		pp-GalNAc-T	148..443	CDD:133004	127/303 (42%)
		Catalytic subdomain B	311..373		38/61 (62%)
		Flexible loop	373..384		3/17 (18%)
		Ricin_B_lectin	459..587	CDD:279046	33/138 (24%)
		RICIN	461..589	CDD:238092	34/138 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3364
OMA	1	1.010	-	-		QHG48703
OrthoDB	1	1.010	-	-		D144590at33208
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.840