DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant8 and CG10000

DIOPT Version :9

Sequence 1:	NP_648800.1	Gene:	Pgant8 / 39715	FlyBaseID:	FBgn0036529	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_651630.3	Gene:	CG10000 / 43394	FlyBaseID:	FBgn0039596	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	177/522 - (33%)
Similarity:	265/522 - (50%)	Gaps:	90/522 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 YNAWLSKRISPERSLYDMRHRSCKK----LKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRT 155
            ||..||..:...|.|...||.||..    |..|:|  .:|||||::|||..|:||||:.||.||:
  Fly    75 YNIHLSNALGLIRKLPVTRHHSCTTRNSILPAPLE--ANVSVVISFHNEARSMLLRTIVSLLSRS 137

  Fly   156 PIQLLREVILVDDGSTQADEKLNDFIK--------------IKFLNMVQHRRITTQVGLMHARVV 206
            |...|.|:||||||| |.|..|.|.:|              :.||      |...::||:.:|..
  Fly   138 PEDYLHELILVDDGS-QRDVTLLDDLKRWMGGVFGSRYRLGLTFL------RNQERMGLIWSRNR 195

  Fly   207 GAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGKP-SRGFFN 270
            ||.||....::|||||.||.:||||||:..:..:.....:|::|.||....:||:|.. .:|.|:
  Fly   196 GASLASGRYVLFLDSHCEVNEGWLEPLLERLALNTNLAVSPLLDPIDPTTLSYRKGNELLKGGFD 260

  Fly   271 W--EFNYIQLPLLKEEAVAMPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKL 333
            |  .|::::..|..:|::.|  |:::|...||:..:.||||.:||.::..|||||.|..||::||
  Fly   261 WSLHFHWLKRQLTNQESLEM--PYQSPAFAGGVLMMSREWFLKLGSFNPYLKIWGGESIELAIKL 323

  Fly   334 WLCGGQILEVPCSRVGHLFRDGN-FQI-RYTNKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANM 396
            |||||||..|||||:||:||..: |.. ..:::..:..::....|.:.:||.||||||:..:|..
  Fly   324 WLCGGQIEIVPCSRIGHIFRRRHAFDFPPQSDRQLSPAQETYLHNSKIIAESWLDEYKNMFYALR 388

  Fly   397 PHLTVIPVGNLAE--QRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYASGVLQSISSPKLC 459
            |....||:.:..:  ||..|.| .|.||:|:|.:::.:....:..|.    |:|.|:   :...|
  Fly   389 PAARRIPLDHTYDELQRMRKER-RCHPFEWYLRHVSPELRMHFDELS----ATGTLR---NEDRC 445

  Fly   460 LD--RKDPSHGQPKLAPCSSDHVFPSPEQYWS-------LTNHRELRSGFYCLEVRNHGVNVHIY 515
            :.  :||   .||.||.|     :.|....||       |:.||||     ||.| ..|:.:.:.
  Fly   446 VHARQKD---SQPILASC-----YLSDITQWSMLRQSGQLSTHREL-----CLAV-GFGMRIALE 496

  Fly   516 QCHGQSGNQFWSFDSKTHQVISGQQQNFR---HCLEAQPEL-------NAVTSSVCDPKNHKQQW 570
            .| |:            ::.:...|:..|   |.|.|:..|       :.:..|.|......|.:
  Fly   497 PC-GR------------NETVRRSQRWVRLGTHLLHAESHLCLDNPLKDRLEMSTCRSHAVSQSF 548

  Fly   571 KF 572
            :|
  Fly   549 QF 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	127/319 (40%)
		pp-GalNAc-T	131..430	CDD:133004	127/319 (40%)
		Ricin_B_lectin	446..570	CDD:279046	34/142 (24%)
		RICIN	448..572	CDD:238092	33/142 (23%)
CG10000	NP_651630.3	pp-GalNAc-T	113..422	CDD:133004	127/318 (40%)
CG10000	NP_651630.3	Ricin_B_lectin	435..548	CDD:279046	34/142 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910