DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant8 and CG7579

DIOPT Version :9

Sequence 1:	NP_648800.1	Gene:	Pgant8 / 39715	FlyBaseID:	FBgn0036529	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	174/516 - (33%)
Similarity:	277/516 - (53%)	Gaps:	35/516 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 TEEQLEAIAKSQRETGYNAWLSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASV 143
            ||..|........:..||||||:||..:|:|.|.|...|.|:.|..||..:||:||....|....
  Fly     2 TETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHT 66

  Fly   144 LLRTLSSLRSRTPIQLLREVILVDDGSTQADEKLNDFIKIKFLNMVQHR-------RITTQVGLM 201
            |||.:.|:.::|...||:|::||.||....|          .:..:.|:       .:.:..|::
  Fly    67 LLRGIYSVITQTSPYLLKEIVLVHDGHPDLD----------LIRHIHHKLPIVIQLEMESSKGII 121

  Fly   202 HARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRR-GKPS 265
            |||:.||.:|..|:||||:.|:|||:|||.||:.|||.:|:|.|.||:|.|..::||||: .:|.
  Fly   122 HARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPE 186

  Fly   266 RGFFNWEFNYIQLPLLKEEAVAMPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELS 330
            :..|:|:.::|.|||.:....::|.|:.:..:.|.:|||.|:||..|||:|:||:.:|.:..|||
  Fly   187 QLAFDWQLDHIFLPLDQHSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELS 251

  Fly   331 LKLWLCGGQILEVPCSRVGHLFRDGNFQIRYT-NKDKNSEKKLISRNYRRVAEIWLDEYKDKLFA 394
            ||:|.|||.||.|||||||.:::....:.:.. |::.:.:   :.:|::||.::||||||...:.
  Fly   252 LKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNPSLQ---VQKNFKRVVDVWLDEYKLHFYR 313

  Fly   395 NMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYASGVLQSISSPKLC 459
            ..|.|..:...:|.:.|||:.||:||.|:|:...:|....|.:.......|..|.:....:|..|
  Fly   314 YNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAPHFC 378

  Fly   460 LDRKDPSHGQPKLAPCSSDHVFPSPEQYWSLTNHRELRSGFYCLEVRNHGVNVHIYQCHGQSGNQ 524
            |..|.   |.|.:..|.|.:.     :.|:||:..:|:.|..||:| ::..||...:|..:....
  Fly   379 LSIKG---GFPVIRKCHSTNF-----EDWTLTSRCQLKHGNMCLDV-DYKNNVRATKCTKKLSKN 434

  Fly   525 FWSFDSKTHQVISGQQQNFRHCLEAQPELNAVTSSVCDPKNHKQQWKFGYLNSQRLQHFWD 585
            .|.::.:....:|    |...||:.......:..|.||....:|:|.|..:...:|.|..|
  Fly   435 PWHYNYQHSSFVS----NGNKCLQIDVNKVGLILSACDSDVTEQRWMFTKVQDFKLDHMRD 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	117/307 (38%)
		pp-GalNAc-T	131..430	CDD:133004	116/307 (38%)
		Ricin_B_lectin	446..570	CDD:279046	29/123 (24%)
		RICIN	448..572	CDD:238092	30/123 (24%)
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	111/296 (38%)
		pp-GalNAc-T	54..349	CDD:133004	116/307 (38%)
		RICIN	367..478	CDD:238092	30/123 (24%)
		Ricin_B_lectin	373..476	CDD:279046	28/115 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276134at2759
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850