Protein Alignment Pgant8 and GALNT18

DIOPT Version :9

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_940918.2
• Gene: GALNT18 / 374378
• HGNCID: 30488
• Length: 607
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 174/605 - (28%)
• Similarity: 284/605 - (46%)
• Gaps: 117/605 - (19%)

  Fly    15 LLLLMAIGSIIYYLYTLKLEGERDESATSTTSRLERDIRDLQAVFE---------SEVIPDLGAL 70
            ::.|:.:|.:..|:.::.:.|:.    .:...:||.|..|...:.|         .:.|.:..|.
Human    23 IICLLYVGWVTNYIASVYVRGQE----PAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAK 83

  Fly    71 GRPAR----------GNWTEE---QLEAIAKSQ-RETGYNAWLSKRISPERSLYDMRHRSCKKLK 121
            ...|.          .:|.:|   :...:|..| :..||||:||.|:..:|.|.|:|...|:.|.
Human    84 PEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLS 148

  Fly   122 YPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQAD--EKLNDFI--- 181
            :| :.||.||:|..:.||..|||||::.|...|||..||:|:|||||.|:..:  |||.:::
Human   149 FP-DSLPEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKV 212

  Fly   182 ---KIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRT 243
               |..|:.:|:|.:   |.||:.:||.|...|.|.|:...|:|||...||.||::..|.|:.:.
Human   213 NSQKPGFIKVVRHSK---QEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKR 274

  Fly   244 CTTPIIDTIDFDNFAYRRGKPSRGFFNWEF--NYIQLPLLKEEAVAMPAPHKNPIMNGGLFAIGR 306
            ..:|..|.|.:|||.......:...|:||.  .|:..|....:.....||.::|.:. |.|.:.|
Human   275 IISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALI-GCFIVDR 338

  Fly   307 EWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNSEKK 371
            ::|.|:|..|:|::::|.|..||.:::|.|||.:..:||||:.|:.|...   .|| :|..:.
Human   339 QYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHK---PYT-EDLTAH-- 397

  Fly   372 LISRNYRRVAEIWLDEYKDKLFA--NMPHL-TVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDF 433
             :.||..||||:|:||:|..::.  |:|.. :.|.:|::..::.|:.:|.||.|:|:|
Human   398 -VRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYL------- 454

  Fly   434 LNLYPIL----DPAEYASGVLQSISSPKLCLDRKDPSHGQPKLAPCSSDHVFPSPEQYWSLTNHR 494
            :::||.:    |...|  ||||:.....||||:.                  |..|
Human   455 VSVYPEMRMYSDIIAY--GVLQNSLKTDLCLDQG------------------PDTE--------- 490

  Fly   495 ELRSGFYCLEVRNHGVNVHI-YQCHGQS-GNQFWSFDSKTHQVISGQ--QQNFRHCL---EAQPE 552
                            ||.| |.|||.: .|.:::...:.|..|...  ..:...||   .::|.
Human   491 ----------------NVPIMYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPR 539

  Fly   553 LNAVTSSVCDPKNHKQQWKF 572
            |  :..|....|..|..|:|
Human   540 L--IECSYAKAKRMKLHWQF 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	109/311 (35%)
		pp-GalNAc-T	131..430	CDD:133004	108/311 (35%)
		Ricin_B_lectin	446..570	CDD:279046	27/130 (21%)
		RICIN	448..572	CDD:238092	28/130 (22%)
GALNT18	NP_940918.2	Catalytic subdomain A	153..267		49/116 (42%)
		pp-GalNAc-T	157..458	CDD:133004	108/318 (34%)
		Catalytic subdomain B	324..385		23/61 (38%)
		RICIN	471..598	CDD:238092	29/132 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810