Protein Alignment Pgant8 and Galnt3

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001015032.2
• Gene: Galnt3 / 366061
• RGDID: 1306443
• Length: 633
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 190/663 - (28%)
• Similarity: 309/663 - (46%)
• Gaps: 174/663 - (26%)

  Fly     8 HKKKVLPLLL-------LMAIGSIIYYLYTLKLEGERDESA--TSTTSRLERDIRDLQAVFE--- 60
            |.|:::.|.:       ...:|::|::...:.:..:|:.|.  :...|::||::::...:|:
  Rat     3 HLKRLVKLHIKRHYHRKFWKLGAVIFFFLVVLILMQREVSVQYSKEESKMERNLKNKNKMFDFML 67

  Fly    61 ------SEVIPDLGALGRPAR------------GNWTEEQLEAI--------------------- 86
                  .:.:|.: .:|.|.:            |.:|..:|:.:
  Rat    68 EAVNNIKDAMPKM-QIGAPIKQNIDVPERPCLQGYYTAAELKPVLDRPPQDSNAPGASGKPFKIT 131

  Fly    87 -----AKSQRETG-----YNAWLSKRISPERSL-YDMRHRSCKKLKYP-MEKLPSVSVVITYHNE 139
                 .:.::|.|     :||:.|.|||..|.| .|.|...|.:.|:. ...||:.||:|.:|||
  Rat   132 HLSPEEQKEKERGETKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNE 196

  Fly   140 EASVLLRTLSSLRSRTPIQLLREVILVDDGSTQ--ADEKLNDFIK----IKFLNMVQHRRITTQV 198
            ..|.||||:.|:...:|..||:|:|||||.|..  ..|||.::||    :|.:.. |.|:
  Rat   197 AWSTLLRTVHSVLYSSPAILLKEIILVDDASVDDYLHEKLEEYIKQFSIVKIVRQ-QERK----- 255

  Fly   199 GLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGK 263
            ||:.||::||.:|.|:.|.|||:|.|...||||||:|.|.|:.....:|.|.:||.:.|.:.:..
  Rat   256 GLITARLLGAAVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPS 320

  Fly   264 P-----SRGFFNW--EFNYIQLP-----LLKEEAVAMPAPHKNPIMNGGLFAIGREWFSELGGYD 316
            |     :||.|:|  .|.:..||     ..|:|..    |.|.|...||||:|.|::|..:|.||
  Rat   321 PYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETY----PIKTPTFAGGLFSISRDYFEHIGSYD 381

  Fly   317 KGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNSEKK---LISRNYR 378
            :.::|||.|..|:|.::|.||||:..:|||.|||:||         :|..::..|   :|:||..
  Rat   382 EEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHVFR---------SKSPHTFPKGTQVIARNQV 437

  Fly   379 RVAEIWLDEYKDKLFANMPHLTVI----PVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLY-P 438
            |:||:|:||||:..:........|    ..|:|:::.::|.||.||.|.|:|:   |.:..:| |
  Rat   438 RLAEVWMDEYKEIFYRRNTDAAKIVKQKSFGDLSKRFEIKKRLQCKNFTWYLN---TIYPEVYVP 499

  Fly   439 ILDPAEYASGVLQSISSPKLCLDRKDPSHGQPKLAPCSSDHVFPSPEQYWSLTNHRELRSGFYCL 503
            .|:|.  .||.::|:..| ||||..:.:.|...|.
  Rat   500 DLNPV--ISGYIKSVGQP-LCLDVGENNQGDKPLI------------------------------ 531

  Fly   504 EVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNFRHCLEAQPELNA----VTSSVCDPK 564
                      :|.|||..|||::.:.:         |:..||.::.:..|:|    |....|..|
  Rat   532 ----------LYTCHGLGGNQYFEYSA---------QREIRHNIQKELCLHATQGVVQLKACVYK 577

  Fly   565 NHK------QQWK 571
            .|:      |.|:
  Rat   578 GHRTIAPGEQIWE 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	124/323 (38%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	28/137 (20%)
Galnt3	NP_001015032.2	pp-GalNAc-T	188..493	CDD:133004	125/326 (38%)
		beta-trefoil_Ricin-like	502..630	CDD:483949	29/141 (21%)