Protein Alignment Pgant8 and Galnt16

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001094333.1
• Gene: Galnt16 / 362760
• RGDID: 1310202
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 199/601 - (33%)
• Similarity: 300/601 - (49%)
• Gaps: 90/601 - (14%)

  Fly     9 KKKVLPLLLLMAIGSIIYYLYTLKLEGERDESATSTTSRLERDIRDLQAVFESEVIPDLGALGRP 73
            :...:.:|.:..|....|||:    :..|..:|:|.....:|.....:.:.|...|| |...|.|
  Rat     5 RANAIAILTVAWILGTFYYLW----QDNRAHAASSGGRGAQRAGGRPEQLREDRTIP-LIVTGTP 64

  Fly    74 ARG-----NWTEEQLEAIAKSQRETGYNAWLSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVV 133
            ::|     ..:.:||:......|:..:|...|.::||:|.:.|.||.||..|.|..: ||:.||:
  Rat    65 SKGFDEKAYLSAKQLKPGEDPYRQHAFNQLESDKLSPDRPIRDTRHYSCPSLSYSSD-LPATSVI 128

  Fly   134 ITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQADE--KLNDFIKIKFLNMVQHRRITT 196
            ||:|||..|.||||:.|:.:|||..|::|:|||||.|:..::  .|....|:|.|      |...
  Rat   129 ITFHNEARSTLLRTVKSVLNRTPAGLIQEIILVDDFSSDPEDCLLLTRIPKVKCL------RNDK 187

  Fly   197 QVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRR 261
            :.||:.:||.||::|.|.||.|||||.||...||:|::..::||:....:||||.|..|||||..
  Rat   188 REGLIRSRVRGADVAGASVLTFLDSHCEVNVEWLQPMLQRVMEDHTRVVSPIIDVISLDNFAYLA 252

  Fly   262 GKPS-RGFFNW--EFNYIQLPLLKEEAVAMPA-PHKNPIMNGGLFAIGREWFSELGGYDKGLKIW 322
            .... ||.|:|  .|.:.|:||.::.....|. |.:.|::.||:|.|.:.||:.||.||..:.||
  Rat   253 ASADLRGGFDWSLHFKWEQIPLEQKMTRTDPTKPIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIW 317

  Fly   323 GAEQFELSLKLWLCGGQILEVPCSRVGHLFR--------DGNFQIRYTNKDKNSEKKLISRNYRR 379
            |.|.||||.::|:|||.:..||||||||:||        :|| .:.|.            ||.:|
  Rat   318 GGENFELSFRVWMCGGSLEIVPCSRVGHVFRKRHPYNFPEGN-ALTYI------------RNTKR 369

  Fly   380 VAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILD-PA 443
            .||:|:||||...:...|.......|::|.:.:.:.::.||.|:|:|:       |:||.|. |.
  Rat   370 TAEVWMDEYKQYYYEARPSAIGKAFGSVATRIEQRKKMDCKSFRWYLE-------NVYPELTVPV 427

  Fly   444 -EYASGVL-QSISSPKLCLDRKDPSHGQPK-------LAPCSSDHVFPSPEQYWSLTNHRELRSG 499
             |...||: |.::    ||:    |.||..       :..|......|.|.|.|..::|...:.|
  Rat   428 KEVLPGVIKQGVN----CLE----SQGQNTAGDLLLGMGICRGSAKSPPPAQAWLFSDHLIQQQG 484

  Fly   500 FYCLE-----VRNHGVNVHIYQCHGQSGNQFW----SFDSKTHQVISGQQQNFRHCLEAQPELNA 555
             .||.     :.:.|..|.:..|:.:.|.|.|    ||   ....:||.      |||.:|.  .
  Rat   485 -KCLAATSTLMSSPGSPVVLQSCNPKEGKQKWRRKGSF---IQHSVSGL------CLETKPA--Q 537

  Fly   556 VTSSVCDPKNHKQQWK 571
            :.::.|......|||:
  Rat   538 LVTNKCQADAQAQQWQ 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	125/312 (40%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	35/144 (24%)
Galnt16	NP_001094333.1	pp-GalNAc-T	126..420	CDD:133004	126/319 (39%)
		beta-trefoil_Ricin-like	426..557	CDD:483949	37/148 (25%)