Protein Alignment Pgant8 and Galnt12

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001413928.1
• Gene: Galnt12 / 313233
• RGDID: 1562001
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 185/600 - (30%)
• Similarity: 275/600 - (45%)
• Gaps: 109/600 - (18%)

  Fly     7 RHKKKVLPLLLLMAIGSIIYYLYTLKLEGERDESATSTT----SRLERDIRDLQAVFESEVIP-- 65
            |.::.:|.||.|..:|:::           |..|.:.|.    :|.....|. :.|.....:|
  Rat    16 RGREALLALLALAGLGAVL-----------RARSRSGTVDPVPTRTPHPGRH-EPVLPRPPLPAD 68

  Fly    66 DLGALGRPARGNWTEEQLEAIAKSQRETGYNAWLSKRISPERSLYDMRHRSCKKLKYPMEKLPSV 130
            .|||.|...|.....|:|....:|.:....|.:||.|||..|.|.:..:..|:::||..:.||..
  Rat    69 ALGAKGEAVRLQLQGEELRLQEESVQRHQINIYLSDRISLHRRLPERWNPLCREVKYDYDNLPKT 133

  Fly   131 SVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQADEK------LNDFIKIKFLNMV 189
            ||||.::||..|.||||:.|:...:|..||.|||||||.|.:...|      |:...|::.:
  Rat   134 SVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKEPLANELSQLPKVRLI--- 195

  Fly   190 QHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDF 254
               |.:.:.||:.||::||..|..:||.|||.|.|..:||||||:..|.|.......|:||.||:
  Rat   196 ---RASKREGLVRARLLGASAARGEVLTFLDCHCECHEGWLEPLLQRIHEKESAVVCPVIDVIDW 257

  Fly   255 DNFAY--RRGKPSRGFFNWEFNYIQLPLLKEEAVAMPAP---HKNPIMNGGLFAIGREWFSELGG 314
            :.|.|  ..|:|..|.|:|...:....:.:.|...|.:|   .::|.|.|||||:.:.:|..||.
  Rat   258 NTFEYLGNSGEPQIGGFDWRLVFTWHVVPQRERKLMRSPIDVIRSPTMAGGLFAVSKRYFEYLGS 322

  Fly   315 YDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNSEKKLISRNYRR 379
            ||.|:::||.|..|.|.::|.|||.:...|||.|||:|..   |..|      |..|.:: |..|
  Rat   323 YDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPK---QAPY------SRSKALA-NSVR 377

  Fly   380 VAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAE 444
            .||:|:|::|:..:...|...:.|.|::.|::.|:.:|.||.||||||       .:||.|...|
  Rat   378 AAEVWMDDFKELYYHRNPQARLEPFGDVTERKKLRAKLQCKDFKWFLD-------TVYPELHVPE 435

  Fly   445 YASGVLQSISSPKL---CLDRKDPSHGQPKLAPCSSDHVFPSPEQYWSLTNHRELRSGFYCLEVR 506
            ...|....:.:..|   |||...||.                        |:.|
  Rat   436 DRPGFFGMLENRGLRGYCLDYNPPSE------------------------NNVE----------- 465

  Fly   507 NHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNFRHCLEAQPELNAVTSSVCD---PKN--- 565
              |..|.:|.|||...|||:.:.|:  |.|....:....|:..:...:.:...:|.   |:|
  Rat   466 --GHQVLLYLCHGMGQNQFFEYTSR--QEIRYNTRQPEACIAVEEGKDVLIMDLCKDTVPENQEF 526

  Fly   566 ---------HKQQWK 571
                     |||..|
  Rat   527 VLQEDGTLVHKQSGK 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	118/309 (38%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	28/144 (19%)
Galnt12	NP_001413928.1	None