DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant8 and Galnt11

DIOPT Version :9

Sequence 1:	NP_648800.1	Gene:	Pgant8 / 39715	FlyBaseID:	FBgn0036529	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001258248.1	Gene:	Galnt11 / 311952	RGDID:	735097	Length:	609	Species:	Rattus norvegicus

Alignment Length:	574	Identity:	192/574 - (33%)
Similarity:	291/574 - (50%)	Gaps:	88/574 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 RDLQAVFESEVIPDLGALGRPARGNWTEEQLEAIAKSQRETG-------------------YNAW 98
            |.|:..|::..:.||       ..|..|:..:.::||..|.|                   :|..
  Rat    66 RVLEPQFKANRMDDL-------MNNNIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHAFNML 123

  Fly    99 LSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREV 163
            :|.|:...|.:.|.|:..|:...||.: ||:.||||.::||..|.||||:.|:..|||..||.|:
  Rat   124 ISNRLGYHRDVPDTRNAECRGKSYPTD-LPTASVVICFYNEAFSALLRTVHSVVDRTPAHLLHEI 187

  Fly   164 ILVDDGSTQADEK--LNDFI------KIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLD 220
            |||||.|...|.|  |:::|      |:|.:..::..      ||:..|::||..|..:||||||
  Rat   188 ILVDDSSDFDDLKGELDEYIQRYLPAKVKVIRNMKRE------GLIRGRMIGAAHATGEVLVFLD 246

  Fly   221 SHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGKPSRGFFNW--EFNYIQLPLLK- 282
            ||.||...||:||:|.||||..|...|:||.|..|..||......||.|||  .|.:..:|:..
  Rat   247 SHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSDL 311

  Fly   283 EEAVAMPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSR 347
            ..|.:..||.::|.|.|||||:.|::|::||.||.|:.|||.|..|:|.::|:|||::..:||||
  Rat   312 GGADSATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSR 376

  Fly   348 VGHLFRDGNFQIRYTNKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRD 412
            |||:||.   :..|.:.:   .:..::.|..|:|.:||||||::.|:..|.|.....||::|:.:
  Rat   377 VGHIFRK---RRPYGSPE---GQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSFGNISERVE 435

  Fly   413 LKNRLHCKPFKWFLDNLATD--------------FLNLYPILDPAEYASGVLQSISSPKLCL--- 460
            |:.:|.|:.|||:|||:..:              |:|..| ..|.....|.|..:.:.| ||
  Rat   436 LRKKLGCQSFKWYLDNVYPEMQVSGPKARLQQPVFINRGP-KRPRVLLRGRLYHLQTNK-CLVAQ 498

  Fly   461 DRKDPSHGQPKLAPCSSDHVFPSPEQYWSLTNHREL-RSGFYCLEVRNHGVN--VHIYQCHGQSG 522
            .|.....|...|..|.    :..|.|.|......|| .:...||::.....:  ..:.:|||..|
  Rat   499 GRSSQKGGLVLLKACD----YGDPTQVWIYNEEHELILNNLLCLDMSETRSSDPPRLMKCHGSGG 559

  Fly   523 NQFWSF--DSKTHQVISGQQQNFRHCLEAQPELNA---VTSSVCDPKNHKQQWK 571
            :|.|:|  :::.:||..||      ||....:::.   |..::||..: .|||:
  Rat   560 SQQWTFGKNNRLYQVSVGQ------CLRVVDQMDQKGYVGMAICDGSS-SQQWR 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	129/309 (42%)
		pp-GalNAc-T	131..430	CDD:133004	131/309 (42%)
		Ricin_B_lectin	446..570	CDD:279046	33/134 (25%)
		RICIN	448..572	CDD:238092	35/135 (26%)
Galnt11	NP_001258248.1	pp-GalNAc-T	155..453	CDD:133004	131/309 (42%)
		Glyco_tranf_2_3	155..383	CDD:290369	105/233 (45%)
		Ricin_B_lectin	484..605	CDD:279046	33/132 (25%)
		RICIN	488..607	CDD:238092	33/131 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346047
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740