DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant8 and Galnt13

DIOPT Version :9

Sequence 1:	NP_648800.1	Gene:	Pgant8 / 39715	FlyBaseID:	FBgn0036529	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_017447163.1	Gene:	Galnt13 / 311039	RGDID:	735044	Length:	571	Species:	Rattus norvegicus

Alignment Length:	572	Identity:	191/572 - (33%)
Similarity:	282/572 - (49%)	Gaps:	88/572 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 ESEVIPDLGA-LGRPARGNWTEEQLEAIAKSQRE--------TGYNAWLSKRISPERSLYDMRHR 115
            |..::|.|.| :.|...|.....:...|.|..:|        ..:|...|..|:..|||.|:|..
  Rat    39 ERSLLPALRAVISRNQEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLE 103

  Fly   116 SCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQADEKLNDF 180
            .||...|| ::||:.||||.:|||..|.||||:.|:.:|:|..||.|||||||.|.:      ||
  Rat   104 GCKTKVYP-DELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASER------DF 161

  Fly   181 IKIKFLNMVQHRRITTQV-------GLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPIL 238
            :|:...|.|:...:..::       ||:.||:.||..:...|:.|||:|.|.|.||||||:|.|.
  Rat   162 LKLTLENYVKTLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIK 226

  Fly   239 EDNRTCTTPIIDTIDFDNFAYRRGKP-SRGFFNWEFNYIQLPLLKEEAVAMPA----PHKNPIMN 298
            ||.:|...||||.|..|.|.|..|.. :.|.|||:.|:...|:.:.|......    |.:.|.|.
  Rat   227 EDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMA 291

  Fly   299 GGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTN 363
            ||||:|.|.:|.|:|.||.|:.|||.|..|:|.::|.|||.:..|.||.|||:||...   .||.
  Rat   292 GGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKAT---PYTF 353

  Fly   364 KDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDN 428
            ......  :|::|.||:||:|:||:||..:...|.:..:..|:::.::.|:..|.||||.|:|:
  Rat   354 PGGTGH--VINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLE- 415

  Fly   429 LATDFLNLYPILD-PAEYAS-GVLQSISSPKLCLD---RKDPS-------HGQPKLAPCSSDHVF 481
                  |:||... |..|.| |.::::.:.: |||   ||:..       ||.
  Rat   416 ------NIYPDSQIPRRYYSLGEIRNVETNQ-CLDNMGRKENEKVGIFNCHGM------------ 461

  Fly   482 PSPEQYWSLTNHRELRSGFYCLEVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNFRHC 546
             ...|.:|.|..:|:|:...||:|......|.:.:||...|||.|.:|::||.::....|:   |
  Rat   462 -GGNQVFSYTADKEIRTDDLCLDVSRLSGPVIMLKCHHMRGNQLWEYDAETHTLVHIITQS---C 522

  Fly   547 LEAQPELNAVTSSVCDPKNH----------KQQWKF-GYLNSQRLQHFWDNV 587
            |.        ...|.|...|          .|:|.. .|..::..::.:.|:
  Rat   523 LS--------MGKVADGSQHLTMETCNDSTLQKWLLRNYTRAEVFRNVFGNL 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	126/310 (41%)
		pp-GalNAc-T	131..430	CDD:133004	126/310 (41%)
		Ricin_B_lectin	446..570	CDD:279046	34/144 (24%)
		RICIN	448..572	CDD:238092	34/143 (24%)
Galnt13	XP_017447163.1	pp-GalNAc-T	118..418	CDD:133004	127/317 (40%)
Galnt13	XP_017447163.1	Ricin_B_lectin	431..548	CDD:395527	33/141 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346053
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740