Protein Alignment Pgant8 and Galntl6

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_017168336.2
• Gene: Galntl6 / 270049
• MGIID: 1913581
• Length: 695
• Species: Mus musculus
• Alignment Length: 625
• Identity: 222/625 - (35%)
• Similarity: 338/625 - (54%)
• Gaps: 84/625 - (13%)

  Fly     7 RHKKKVLPLLLLMAIGSI------IYYLY---------------TLKLEGERDESATSTTSRLER 50
            |.:|:.|.:.||..:..|      ::.||               |..| |..|....|.|..|.|
Mouse    97 RKQKRFLQMTLLFTVALIFLPNIGLWSLYKDKHLVKSAEPAEHQTFPL-GLGDGQFYSWTDGLRR 160

  Fly    51 -DIRDLQAVFESEVIPDLGALGRPARGNWTEEQLEAIAKSQRETGYNAWLSKRISPERSLYDMRH 114
             |..|.:::....:....|..|:|.  ..|||..:..|  .||.|:|.::|..|:.||||.|:||
Mouse   161 KDWHDYESIQRDALRSGKGEHGKPY--PLTEEDRDDSA--YRENGFNIFVSNNIALERSLPDIRH 221

  Fly   115 RSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQ--ADEKL 177
            .:||...| :|:||:.|::|.:|||..:.||||:.|:.:|||..|:.|:|||||.|.:  ..:||
Mouse   222 ANCKHKMY-LERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHLKDKL 285

  Fly   178 ND----FIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPIL 238
            .|    |.|::.:      |...:.||:..|::||.:|..:||.|||||.||...||.||:..|.
Mouse   286 EDYMARFSKVRIV------RTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIA 344

  Fly   239 EDNRTCTTPIIDTIDFDNFAY--RRGKPSRGFFNWEFNYIQLPLLKEEAVAMPA-PHKNPIMNGG 300
            .:::|...|:||.||.::|.|  :.|...||.|:||..|.::|:..|...|.|: |.::|:|.||
Mouse   345 LNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGG 409

  Fly   301 LFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKD 365
            |||:.|:||.||||||.||:|||.||:|:|.|:|:|||::.:||||||||::|.   .:.|....
Mouse   410 LFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRK---YVPYKVPS 471

  Fly   366 KNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLA 430
            ..|    ::||.:||||.|:||:.:.::...|....:..|:::.|::|:.||.||.||||:..:|
Mouse   472 GTS----LARNLKRVAETWMDEFAEYIYQRRPEYRHLSTGDISAQKELRKRLKCKDFKWFMAAVA 532

  Fly   431 TDFLNLYPILDPAEYASGVLQSISSPKLCLDRKDPSHG-QPKLAPCSSDHVFPSPEQYWSLTNHR 494
            .|....||.::|...|.|.::|::: .||:|.|..:.| :.:|..|..|    ..|:.||   |.
Mouse   533 WDVPKYYPPVEPLPAAWGEIRSVAA-NLCVDSKHGATGTELRLDVCVKD----GSERTWS---HE 589

  Fly   495 EL---------RSG------FYCLEVRNHGVNVHIYQCHGQSGNQFWSF-DSKT--HQVISGQQQ 541
            :|         |.|      .:||:..:|...|.:|.|||..|||.|.: :.:|  |.|.:.
Mouse   590 QLFTFGWREDIRPGEPLHTRKFCLDAISHSSPVTLYDCHGMKGNQLWGYREDRTLFHPVSNS--- 651

  Fly   542 NFRHCLEAQPELNAVTSSVCDPKNHKQQWKFGYLNSQRLQ 581
                |::..|....:..:.|||.:..|||.|.::|...|:
Mouse   652 ----CMDCNPSEKKIFMARCDPLSETQQWIFEHINMTVLE 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	129/307 (42%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	41/146 (28%)
Galntl6	XP_017168336.2	pp-GalNAc-T	237..532	CDD:133004	129/307 (42%)
		beta-trefoil_Ricin_GALNTL6	543..688	CDD:467355	45/160 (28%)