Protein Alignment Pgant8 and Galnt5

DIOPT Version :9

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_766443.2
• Gene: Galnt5 / 241391
• MGIID: 2179403
• Length: 930
• Species: Mus musculus
• Alignment Length: 559
• Identity: 180/559 - (32%)
• Similarity: 280/559 - (50%)
• Gaps: 96/559 - (17%)

  Fly    53 RDLQAVFESEVIPDLGALGRP----------ARGNWTEEQLEAIAKSQRETGYNAWLSKRISPER 107
            |||.|.         |..|||          |...|            :|..:|.:||..|..:|
Mouse   423 RDLNAP---------GQFGRPVVVPPEKKKEAEQRW------------KEGNFNVYLSDLIPVDR 466

  Fly   108 SLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQ 172
            ::.|.|...|.: :.....||:.|:::.:.:|..|.|||::.|:.:|:|..|::|::||||.||:
Mouse   467 AIEDTRPAGCAE-QLVHNDLPTTSIIMCFVDEVWSALLRSVHSVLNRSPPHLIKEILLVDDFSTK 530

  Fly   173 ------ADEKLNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLE 231
                  .|:.::.|.|::.|      |:..:.||:.||:.||:.|..|||.|||||||...||||
Mouse   531 EYLKADLDKYMSQFPKVRIL------RLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLE 589

  Fly   232 PLIAPILEDNRTCTTPIIDTID--------FDNFAYRRGKPSRGFFNWEFNY----IQLPLLKEE 284
            ||:..:..:.:....|:|:.|:        .|||       .||.|.|..|:    |...::.:.
Mouse   590 PLLERVYLNRKKVACPVIEVINDKDMSYMTVDNF-------QRGVFTWPMNFGWKTIPPDVVAKN 647

  Fly   285 AVAMPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVG 349
            .:......:.|:|.||||:|.:.:|.|||.||.||.:||.|..|||.|:|:|||:|..:||||||
Mouse   648 GIKETDIIRCPVMAGGLFSIDKSYFYELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVG 712

  Fly   350 HLFRDGNFQIRYT-NKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHL--TVIPVGNLAEQR 411
            |:||:.|   .|: .||:   .|.:.||..||||:|||:|::..:.:..||  ..:.||||.:||
Mouse   713 HIFRNDN---PYSFPKDR---MKTVERNLVRVAEVWLDDYRELFYGHGDHLIDQGLDVGNLTQQR 771

  Fly   412 DLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYASGVLQSISSPKLCLDRKDPSHGQPKLAPCS 476
            :|:.:|.||.|||:|||:..|      :..|...|||||.:::..| |:..::.:   ..|..|.
Mouse   772 ELRKKLKCKSFKWYLDNVFPD------LKAPVVRASGVLINMALGK-CVSIENIT---VTLEDCD 826

  Fly   477 SDHVFPSPEQYWSLTNHRELRSGFYCLEVRNHGVNVHIYQCHGQSGNQFWSFDSKT--------H 533
            ..    |..|.::.|..|.::.|.:|:.......::.:|.|..::....|...|.:        |
Mouse   827 GS----SQLQQFNYTWVRLIKHGEWCVAPIPEKGSLTLYHCDNRNNRLKWLHKSASAFHPELVDH 887

  Fly   534 QVISGQQQNFRHCLEAQPELNAVTSSVCDPKNHKQQWKF 572
            .|....||..  |:|.......:..:.|:|...:|:|||
Mouse   888 IVFENYQQLL--CMEGNFSQKTLKLAACNPMELQQKWKF 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	124/319 (39%)
		pp-GalNAc-T	131..430	CDD:133004	126/319 (39%)
		Ricin_B_lectin	446..570	CDD:279046	28/131 (21%)
		RICIN	448..572	CDD:238092	27/131 (21%)
Galnt5	NP_766443.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..209
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..381
		Catalytic subdomain A	485..594		47/114 (41%)
		pp-GalNAc-T	489..790	CDD:133004	126/319 (39%)
		Catalytic subdomain B	654..716		34/61 (56%)
		RICIN	805..925	CDD:214672	26/130 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810