Protein Alignment Pgant8 and gly-7

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_503512.1
• Gene: gly-7 / 178661
• WormBaseID: WBGene00001632
• Length: 601
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 204/616 - (33%)
• Similarity: 317/616 - (51%)
• Gaps: 70/616 - (11%)

  Fly     5 IWRHKKKVLPLLLLMAIGSIIYYLYTLKLEGERDESATSTTSRLERDIRDLQAVFESEVI--PDL 67
            :||  ::...:...:.:|.::.:.:....:|....|..|.::..:.|  ||..:...|:.  ||.
 Worm    13 LWR--QRGCRVATYICLGVLVLFGFVYNSKGNSMSSIKSDSAAQQFD--DLDDLTNKELPGGPDP 73

  Fly    68 GALGRPAR-GNW----------------------TEEQLEAIAKSQRETGYNAWLSKRISPERSL 109
            ..:.|.:. ||:                      .||.:.|...:::|.|:|.::|..||..|::
 Worm    74 NTIFRGSELGNYEPKEPEIPSNQPGEHGKPVPVTDEEGMAAGRAAEKEFGFNTYVSDMISMNRTI 138

  Fly   110 YDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQ-- 172
            .|:|...||...|| ||||:||||:.:|||..:.||||:.|:..|:|.:|:.:|::|||.|.:
 Worm   139 PDIRPEECKHWDYP-EKLPTVSVVVVFHNEGWTPLLRTVHSVLLRSPPELIEQVVMVDDDSDKPH 202

  Fly   173 ADEKLNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPI 237
            ..|||:.:: .:|...|...|...:.||::||.:||:.:..:|::|||:|.||...||.||:|||
 Worm   203 LKEKLDKYV-TRFNGKVIVVRTEQREGLINARSIGAKHSTGEVVLFLDAHCEVNTNWLPPLLAPI 266

  Fly   238 LEDNRTCTTPIIDTIDFDNFAYRR--GKPS---RGFFNWEFNYIQLPLLKEEAVAM---PAPHKN 294
            ..:.:..|.|:||.||.:::.||.  |.|:   .|.|.|...|.:..:.:.|....   ..|.::
 Worm   267 KRNRKVMTVPVIDGIDSNSWEYRSVYGSPNAHHSGIFEWGLLYKETQITERETAHRKHNSQPFRS 331

  Fly   295 PIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRD----- 354
            |...||||||.|.||.|||.||:||:|||.||:|||.|:|.|||.|:.||||.|||::|.
 Worm   332 PTHAGGLFAINRLWFKELGYYDEGLQIWGGEQYELSFKIWQCGGGIVFVPCSHVGHVYRSHMPYS 396

  Fly   355 -GNFQIRYTNKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLH 418
             |.|          |.|.:||.|..||.:.|:|:|........|..|.:..|:::.|..|:::|.
 Worm   397 FGKF----------SGKPVISINMMRVVKTWMDDYSKYYLTREPQATNVNPGDISAQLALRDKLQ 451

  Fly   419 CKPFKWFLDNLATDFLNLYPILDPAEYASGVLQSISSPKLCLDRKDPSHGQPKLAPCSSDHVFPS 483
            ||.|||:::|:|.|.|..||:|.|.: ..|..::.::.| ||||.....|......|   |.: .
 Worm   452 CKSFKWYMENVAYDVLKSYPMLPPND-VWGEARNPATGK-CLDRMGGIPGPMGATGC---HGY-G 510

  Fly   484 PEQYWSLTNHRELRSGFYCLEVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNFRHCLE 548
            ..|...|....::..|.:||..  :|:.:....|...:.|.|||:|.||.|:|..|:   |.|:.
 Worm   511 GNQLIRLNVQGQMAQGEWCLTA--NGIRIQANHCVKGTVNGFWSYDRKTKQIIHSQK---RQCIT 570

  Fly   549 AQPELNAVTSSVCDPKNHKQQ--WKFGYLNS 577
            .....:.||...|...|.:|:  ||..|.:|
 Worm   571 VSESGSEVTLQTCTEDNERQKFVWKEFYQSS 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	124/314 (39%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	35/129 (27%)
gly-7	NP_503512.1	pp-GalNAc-T	159..463	CDD:133004	124/314 (39%)
		beta-trefoil_Ricin_GALNT7	475..596	CDD:467315	35/131 (27%)