Protein Alignment Pgant8 and gly-5

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001379253.1
• Gene: gly-5 / 176736
• WormBaseID: WBGene00001630
• Length: 626
• Species: Caenorhabditis elegans
• Alignment Length: 665
• Identity: 208/665 - (31%)
• Similarity: 300/665 - (45%)
• Gaps: 141/665 - (21%)

  Fly     9 KKKVLPLLLLMA---IGSIIYYLYTLKLEGERDESATSTTSRLERDIRDL--------------- 55
            ||.:|.:|||:.   |.|:|::..|     ..|.|...:.:.|...|.:.
 Worm     6 KKAILKVLLLVPVFWICSLIFFAAT-----SNDSSQIGSNNDLANKIAEANFHPKAAKQDVIQGF 65

  Fly    56 ------QAVFESEVIPD-----------------------------LGALGRPARGNWTEEQLEA 85
                  :.|.|:..:.:                             .|.||:....:.|:...|.
 Worm    66 GPPIEPEPVVENNKVEEEEQPGGNLAKPKFMVDPNDPIYKKGDAAQAGELGKAVVVDKTKLSTEE 130

  Fly    86 IAKSQR---ETGYNAWLSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRT 147
            .||..:   ...:|.:.|..||..|:|.......||..|| .|.||..||:|.:|||..||||||
 Worm   131 KAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKY-NENLPRTSVIICFHNEAWSVLLRT 194

  Fly   148 LSSLRSRTPIQLLREVILVDDGSTQADEK--LNDFI-----KIKFLNMVQHRRITTQVGLMHARV 205
            :.|:..|||..||.||:||||.|.....|  |.:::     |:|.|.|.:..      ||:.||:
 Worm   195 VHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQFGGKVKILRMEKRE------GLIRARL 253

  Fly   206 VGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAYRRGK---PSRG 267
            .||.:|..:||.:||||.|..:||:|||:..|..|..|...|:||.||.:.|.|...|   .|.|
 Worm   254 RGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVG 318

  Fly   268 FFNW--EFNYIQLPLLKEEAVAMPA-PHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFEL 329
            .|:|  :||:..:|....:....|. |.::|.|.||||:|.:::|.:||.||.|..|||.|..||
 Worm   319 GFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLEL 383

  Fly   330 SLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNSEKK------LISRNYRRVAEIWLDEY 388
            |.|:|:|||.:..||||.|||:||            |.|..|      ::.||..|:||:|||:|
 Worm   384 SFKIWMCGGTLEIVPCSHVGHVFR------------KRSPYKWRTGVNVLKRNSIRLAEVWLDDY 436

  Fly   389 KDKLFANMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYP-ILDPAE-YASG-VL 450
            |...:..:.: .:...|:::.::.|:..|.||.|||:||       |:|| :..|.| .|.| |.
 Worm   437 KTYYYERINN-QLGDFGDISSRKKLREDLGCKSFKWYLD-------NIYPELFVPGESVAKGEVR 493

  Fly   451 QSISSPKLCLD-------RKDP-----SHGQPKLAPCSSDHVFPSPEQYWSLTNHRELRSGFYCL 503
            .|...|..|||       :..|     .|||             ...|||.|:...|:|....|:
 Worm   494 NSAVQPARCLDCMVGRHEKNRPVGTYQCHGQ-------------GGNQYWMLSKDGEIRRDESCV 545

  Fly   504 EVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNFRHCLEAQPELNAVTSSVCDPKNHKQ 568
            :..  |.:|.::.|||..|||.|.::..|.::.....|......:...:|..|.....||..|
 Worm   546 DYA--GSDVMVFPCHGMKGNQEWRYNHDTGRLQHAVSQKCLGMTKDGAKLEMVACQYDDPYQH-- 606

  Fly   569 QWKF-GYLNSQRLQH 582
             ||| .|..::.::|
 Worm   607 -WKFKEYNEAKAIEH 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	127/317 (40%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	38/141 (27%)
gly-5	NP_001379253.1	pp-GalNAc-T	178..477	CDD:133004	128/324 (40%)
		beta-trefoil_Ricin_Pgant9-like	485..610	CDD:467340	38/142 (27%)