Protein Alignment Pgant8 and gly-3

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_498722.1
• Gene: gly-3 / 176112
• WormBaseID: WBGene00001628
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 633
• Identity: 195/633 - (30%)
• Similarity: 290/633 - (45%)
• Gaps: 121/633 - (19%)

  Fly    17 LLMAIGSIIYYLYTLKLEGERDESATSTTSRLERDIRDLQAVFESEVIP-----DLGALGRPARG 76
            ||:.:..:.|||          :.:||.......|.|.|......|.:|     |......|.:.
 Worm    23 LLIDVVILFYYL----------DPSTSQQQPFPEDNRILNRARRIEPLPPAAQHDSDPDAHPIQP 77

  Fly    77 NWTEEQLEAIAK--------------------SQRETG-------------------YNAWLSKR 102
            ...|:|:..:.|                    .|..||                   :|...|:.
 Worm    78 EKQEKQVYPVDKETANQLRKLMETQAFGPGYHGQGGTGVTVPEDKKTIKEKRFLENQFNVVASEM 142

  Fly   103 ISPERSLYDMRHRSCK----KLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREV 163
            ||..|:|.|.|..:|:    .||  ...:|..|::|.:|||..:.|||||.|:.:|:|..||.|:
 Worm   143 ISVNRTLPDYRSDACRTSGNNLK--TAGMPKTSIIIVFHNEAWTTLLRTLHSVINRSPRHLLEEI 205

  Fly   164 ILVDDGSTQ--ADEKLNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVT 226
            |||||.|.:  ..:.|:.:||: |...:....:..:.||:.||:.|:|:|...:|:|||:|||||
 Worm   206 ILVDDKSDRDYLVKPLDSYIKM-FPIPIHLVHLENRSGLIRARLTGSEMAKGKILLFLDAHVEVT 269

  Fly   227 KGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAY-RRGKPSRGFFNWEFNYIQLPLLKEE----AV 286
            .||||||::.:.||.:....||||.|..|.|.| ...:.:.|.|||..|:....:.|.|    ..
 Worm   270 DGWLEPLVSRVAEDRKRVVAPIIDVISDDTFEYVTASETTWGGFNWHLNFRWYAVPKRELNRRGS 334

  Fly   287 AMPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHL 351
            ....|.:.|.:.||||||.:::|.::|.||:|:::||.|..|:|.::|:|||.:...|||||||:
 Worm   335 DRSMPIQTPTIAGGLFAIDKQFFYDIGSYDEGMQVWGGENLEISFRVWMCGGSLEIHPCSRVGHV 399

  Fly   352 FRDGNFQIRYTNKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNR 416
            ||.   |..||  ......|:|..|..|.||:|:||||...:..:|....:..|:::|::.|:..
 Worm   400 FRK---QTPYT--FPGGTAKVIHHNAARTAEVWMDEYKAFFYKMVPAARNVEAGDVSERKKLRET 459

  Fly   417 LHCKPFKWFLDNLATDFLNLYPILD-PAEYAS-GVLQSISSPKLCLDRKDPSHGQ-PKLAPCSSD 478
            |.||.|||:|:       |:||... ||::.| |.:.:..:.| |:|......|| |.:..|..
 Worm   460 LQCKSFKWYLE-------NIYPEAPLPADFRSLGAIVNRFTEK-CVDTNGKKDGQAPGIQACHG- 515

  Fly   479 HVFPSPEQYWSLTNHRELRSGFYCL---EVRNHG------------VNV-HIYQCHGQSGNQFWS 527
               ....|.||||...|:||...||   .|...|            :|| |::....|:|.   .
 Worm   516 ---AGGNQAWSLTGKGEIRSDDLCLSSGHVYQIGSELKLERCSVSKINVKHVFVFDDQAGT---L 574

  Fly   528 FDSKTHQVISGQQQNFRHCLEAQPELNAVTSSVCDPKNHKQQWKF-GY 574
            ...||.:.::|..|.             ||...|......|.|:. ||
 Worm   575 LHKKTGKCVTGADQR-------------VTLDECGLGRKDQMWQLEGY 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	121/305 (40%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	35/146 (24%)
gly-3	NP_498722.1	pp-GalNAc-T	173..473	CDD:133004	122/312 (39%)
		beta-trefoil_Ricin_GALNT1-like	481..608	CDD:467311	35/147 (24%)