Protein Alignment Pgant8 and GALNT13

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001363332.1
• Gene: GALNT13 / 114805
• HGNCID: 23242
• Length: 571
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 192/567 - (33%)
• Similarity: 281/567 - (49%)
• Gaps: 89/567 - (15%)

  Fly    60 ESEVIPDLGA-LGRPARGNWTEEQLEAIAKSQRE--------TGYNAWLSKRISPERSLYDMRHR 115
            |..::|.|.| :.|...|.....:...|.|..:|        ..:|...|..|:..|||.|:|..
Human    39 ERSLLPALRAVISRNQEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLE 103

  Fly   116 SCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGSTQADEKLNDF 180
            .||...|| ::||:.||||.:|||..|.||||:.|:.:|:|..||.|||||||.|.:      ||
Human   104 GCKTKVYP-DELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASER------DF 161

  Fly   181 IKIKFLNMVQHRRITTQV-------GLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPIL 238
            :|:...|.|::..:..::       ||:.||:.||..:...|:.|||:|.|.|.||||||:|.|.
Human   162 LKLTLENYVKNLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIK 226

  Fly   239 EDNRTCTTPIIDTIDFDNFAYRRGKP-SRGFFNWEFNYIQLPLLKEEAVAMPA----PHKNPIMN 298
            ||.:|...||||.|..|.|.|..|.. :.|.|||:.|:...|:.:.|......    |.:.|.|.
Human   227 EDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMA 291

  Fly   299 GGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTN 363
            ||||:|.|.:|.|:|.||.|:.|||.|..|:|.::|.|||.:..|.||.|||:||...   .||.
Human   292 GGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKAT---PYTF 353

  Fly   364 KDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGNLAEQRDLKNRLHCKPFKWFLDN 428
            ......  :|::|.||:||:|:||:||..:...|.:..:..|:::.::.|:..|.||||.|:|:
Human   354 PGGTGH--VINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLE- 415

  Fly   429 LATDFLNLYPILD-PAEYAS-GVLQSISSPKLCLD---RKDPS-------HGQPKLAPCSSDHVF 481
                  |:||... |..|.| |.::::.:.: |||   ||:..       ||.
Human   416 ------NIYPDSQIPRRYYSLGEIRNVETNQ-CLDNMGRKENEKVGIFNCHGM------------ 461

  Fly   482 PSPEQYWSLTNHRELRSGFYCLEVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNFRHC 546
             ...|.:|.|..:|:|:...||:|......|.:.:||...|||.|.:|::||.::....|:   |
Human   462 -GGNQVFSYTADKEIRTDDLCLDVSRLNGPVIMLKCHHMRGNQLWEYDAETHTLLHIITQS---C 522

  Fly   547 LEAQPELNAVTSSVCDPKNHK----------QQWKFGYLNSQRLQHF 583
            |.        .:.|.|...|.          |:|..  .|..|::.|
Human   523 LS--------VNKVADGSQHPTVETCNDSTLQKWLL--RNYTRMEIF 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	126/310 (41%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	36/148 (24%)
GALNT13	NP_001363332.1	pp-GalNAc-T	118..418	CDD:133004	127/317 (40%)
		beta-trefoil_Ricin-like	425..552	CDD:483949	36/153 (24%)