Protein Alignment Pgant8 and GALNT5

DIOPT Version :9

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_016858726.1
• Gene: GALNT5 / 11227
• HGNCID: 4127
• Length: 956
• Species: Homo sapiens
• Alignment Length: 587
• Identity: 189/587 - (32%)
• Similarity: 293/587 - (49%)
• Gaps: 104/587 - (17%)

  Fly    38 DESATSTTSRLERDI--RDLQAVFESEVIPDLGALGRPA---RGNWTEEQLEAIAKSQRETGYNA 97
            ::|.|....|::..:  ||.:|.         |..|||.   .|.  |::.|   :..:|..:|.
Human   416 EDSGTHQVLRIDVTLSPRDPKAP---------GQFGRPVVVPHGK--EKEAE---RRWKEGNFNV 466

  Fly    98 WLSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLRE 162
            :||..|..:|::.|.|...|.: :.....||:.||::.:.:|..|.|||::.|:.:|:|..|::|
Human   467 YLSDLIPVDRAIEDTRPAGCAE-QLVHNNLPTTSVIMCFVDEVWSTLLRSVHSVINRSPPHLIKE 530

  Fly   163 VILVDDGSTQ------ADEKLNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVLVFLDS 221
            ::||||.||:      .|:.::.|.|::.|      |:..:.||:.||:.||:.|..|||.||||
Human   531 ILLVDDFSTKDYLKDNLDKYMSQFPKVRIL------RLKERHGLIRARLAGAQNATGDVLTFLDS 589

  Fly   222 HVEVTKGWLEPLIAPILEDNRTCTTPIIDTID--------FDNFAYRRGKPSRGFFNWEFNY--- 275
            |||...||||||:..:....:....|:|:.|:        .|||       .||.|.|..|:
Human   590 HVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNF-------QRGIFVWPMNFGWR 647

  Fly   276 -IQLPLLKEEAVAMPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQ 339
             |...::.:..:......:.|:|.||||:|.:.:|.|||.||.||.:||.|..|||.|:|:|||:
Human   648 TIPPDVIAKNRIKETDTIRCPVMAGGLFSIDKSYFFELGTYDPGLDVWGGENMELSFKVWMCGGE 712

  Fly   340 ILEVPCSRVGHLFRDGNFQIRYT-NKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHL--TV 401
            |..:|||||||:||:.|   .|: .||:   .|.:.||..||||:||||||:..:.:..||  ..
Human   713 IEIIPCSRVGHIFRNDN---PYSFPKDR---MKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQG 771

  Fly   402 IPVGNLAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYASGVLQSISSPKLCLDRKDPS 466
            :.||||.:||:|:.:|.||.|||:|:|:..|      :..|...|||||.:::..| |:..::.:
Human   772 LDVGNLTQQRELRKKLKCKSFKWYLENVFPD------LRAPIVRASGVLINVALGK-CISIENTT 829

  Fly   467 HGQPKLAPCSSDHVFPSPE-QYWSLTNHRELRSGFYCL-EVRNHGVNVHIYQCHGQSGNQFWSFD 529
               ..|..|..     |.| |.::.|..|.::.|.:|: .:.:.|. |.::.|..::....|...
Human   830 ---VILEDCDG-----SKELQQFNYTWLRLIKCGEWCIAPIPDKGA-VRLHPCDNRNKGLKWLHK 885

  Fly   530 SKT------------------------HQVISGQQQNFRHCLEAQPELNAVTSSVCDPKNHKQQW 570
            |.:                        |.|....||..  |||.......:..:.|||....|:|
Human   886 STSVFHPELLSNSACGSFPALLSLQVNHIVFENNQQLL--CLEGNFSQKILKVAACDPVKPYQKW 948

  Fly   571 KF 572
            ||
Human   949 KF 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	127/319 (40%)
		pp-GalNAc-T	131..430	CDD:133004	128/319 (40%)
		Ricin_B_lectin	446..570	CDD:279046	32/149 (21%)
		RICIN	448..572	CDD:238092	31/149 (21%)
GALNT5	XP_016858726.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810