Protein Alignment Pgant8 and POC1B-GALNT4

DIOPT Version :9

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001186710.1
• Gene: POC1B-GALNT4 / 100528030
• HGNCID: 42957
• Length: 575
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 173/553 - (31%)
• Similarity: 263/553 - (47%)
• Gaps: 92/553 - (16%)

  Fly    35 GERDESATSTTSRLERDIRDLQAVFESEVIPD---LGALGRPARGNWTEEQLEAIAKSQRET--- 93
            |...|..:...|.|:::..||......:...|   ||..|:.::....|::|    |.|.|.
Human    36 GRARELGSRRLSDLQKNTEDLSRPLYKKPPADSRALGEWGKASKLQLNEDEL----KQQEELIER 96

  Fly    94 -GYNAWLSKRISPERSLYDMRHRSCKKLKYPMEKLPSVSVVITYHNEEASVLLRTLSSLRSRTPI 157
             ..|.:||.|||..|.:.|.|...||..|:....||:.||:|.::||..|.||||:.|:...:|.
Human    97 YAINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPA 161

  Fly   158 QLLREVILVDDGS------TQADEKLNDFIKIKFLNMVQHRRITTQVGLMHARVVGAELALADVL 216
            .||:|:|||||.|      ||.:..:::..:::.:      |...:.||:.||::||..|..|||
Human   162 VLLKEIILVDDLSDRVYLKTQLETYISNLDRVRLI------RTNKREGLVRARLIGATFATGDVL 220

  Fly   217 VFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDTIDFDNFAY--RRGKPSRGFFNWEFNYIQLP 279
            .|||.|.|...||||||:..|..|......|:|||||::.|.:  :.|:|..|.|:|...:....
Human   221 TFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTFQWHS 285

  Fly   280 LLKEE---AVAMPAPHKNPIMNGGLFAIGREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQIL 341
            :.|:|   .::...|.::|.|.|||||:.:::|..||.||.|:::||.|..|||.::|.|||::.
Human   286 VPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLE 350

  Fly   342 EVPCSRVGHLFRDGNFQIRYTNKDKNSEKKLISRNYRRVAEIWLDEYKDKLFANMPHLTVIPVGN 406
            ..|||.|||:|          .|.....:....:|..|.||:|:||||:..:...|.......|:
Human   351 IHPCSHVGHVF----------PKRAPYARPNFLQNTARAAEVWMDEYKEHFYNRNPPARKEAYGD 405

  Fly   407 LAEQRDLKNRLHCKPFKWFLDNLATDFLNLYPILDPAEYASGVLQSISSPKLCLDRKDPSHGQPK 471
            ::|::.|:.||.||.|.|:|.|:   |.||:...|...: .|.::|......|||...|.:.
Human   406 ISERKLLRERLRCKSFDWYLKNV---FPNLHVPEDRPGW-HGAIRSRGISSECLDYNSPDNN--- 463

  Fly   472 LAPCSSDHVFPSPEQYWSLTNHRELRSGFYCLEVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVI 536
                      |:                         |.|:.::.||||.||||:.:       .
Human   464 ----------PT-------------------------GANLSLFGCHGQGGNQFFEY-------T 486

  Fly   537 SGQQQNFRH----CLEAQPELNAVTSSVCDPKN 565
            |.::..|..    |.|...:.|.|....| ||:
Human   487 SNKEIRFNSVTELCAEVPEQKNYVGMQNC-PKD 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	GT2	128..427	CDD:224137	113/309 (37%)
		pp-GalNAc-T	131..430	CDD:133004	114/309 (37%)
		Ricin_B_lectin	446..570	CDD:279046	26/124 (21%)
		RICIN	448..572	CDD:238092	26/122 (21%)
POC1B-GALNT4	NP_001186710.1	WcaA	131..427	CDD:223539	115/311 (37%)
		pp-GalNAc-T	135..429	CDD:133004	114/312 (37%)
		RICIN	443..573	CDD:238092	26/122 (21%)
		Ricin_B_lectin	443..571	CDD:279046	26/122 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810