Protein Alignment Pgant8 and galnt3

DIOPT Version :10

• Sequence 1: NP_648800.1
• Gene: Pgant8 / 39715
• FlyBaseID: FBgn0036529
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_021334717.1
• Gene: galnt3 / 100331984
• ZFINID: ZDB-GENE-120313-1
• Length: 625
• Species: Danio rerio
• Alignment Length: 552
• Identity: 179/552 - (32%)
• Similarity: 276/552 - (50%)
• Gaps: 90/552 - (16%)

  Fly    68 GALGRPARGNWTEEQLEAIAKSQRETG-----YNAWLSKRISPERSL-YDMRHRSCKKLKY-PME 125
            ||.|:.    :..:.|.:..:.::|.|     :|.:.|.|||..|.| .|.|...|.:..: ...
Zfish   116 GASGKA----FHTDNLSSSEQKEKERGEEKHCFNLYASDRISLSRDLGPDTRPPECIEQTFRRCP 176

  Fly   126 KLPSVSVVITYHNEEASVLLRTLSSLRSRTPIQLLREVILVDDGST--QADEKLNDFIK-IKFLN 187
            .||:.||:|.:|||..|.||||:.|:...:|...|:|:|||||.|.  ...:||::|:| :..:.
Zfish   177 PLPTTSVIIVFHNEAWSTLLRTVYSVLHTSPALFLKEIILVDDASVDEHLKDKLDEFLKQLHIVR 241

  Fly   188 MV-QHRRITTQVGLMHARVVGAELALADVLVFLDSHVEVTKGWLEPLIAPILEDNRTCTTPIIDT 251
            :| ||.|    .||:.||::||.:|..|.|.|||:|.|...||||||:|.|.|::....:|.|.|
Zfish   242 VVRQHER----KGLITARLLGASVATGDTLTFLDAHCECFHGWLEPLLARIAENSSAVVSPDITT 302

  Fly   252 IDFDNFAYRRGKP-----SRGFFNW--EFNYIQLP-----LLKEEAVAMPAPHKNPIMNGGLFAI 304
            ||.:.|.:.:..|     :||.|:|  .|.:..||     ..|:|..    |.|.|...||||:|
Zfish   303 IDLNTFEFMKPSPYGQHHNRGNFDWGLSFGWETLPDHERRRRKDETY----PIKTPTFAGGLFSI 363

  Fly   305 GREWFSELGGYDKGLKIWGAEQFELSLKLWLCGGQILEVPCSRVGHLFRDGNFQIRYTNKDKNSE 369
            .|::|..:|.||:.::|||.|..|:|.::|.||||:..:|||.|||:||        |.......
Zfish   364 SRDYFYHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIIPCSVVGHVFR--------TKSPHTFP 420

  Fly   370 K--KLISRNYRRVAEIWLDEYKDKLFANMPHLTVI----PVGNLAEQRDLKNRLHCKPFKWFLDN 428
            |  ::|:||..|:||:|:|:||:..:........|    ..|:::.:.||:.||.||.|.|:|.|
Zfish   421 KGTQVIARNQVRLAEVWMDDYKEIFYRRNQQAAQIAKEHSFGDVSRRVDLRERLQCKSFSWYLKN 485

  Fly   429 LATDFLNLYPILDPAEYASGVLQSISSPKLCLDRKDPSHGQPKLA--PCSSDHVFPSPEQYWSLT 491
            :..:.  ..|.|:|.::  |.::::.. :.|||..:.:.|...|.  ||..    ....||:..:
Zfish   486 VYPEV--FMPDLNPLQF--GAIRNMGK-EACLDVGESNEGGKPLIMYPCHG----MGGNQYFEYS 541

  Fly   492 NHRELRSGF---YCLEVRNHGVNVHIYQCHGQSGNQFWSFDSKTHQVISGQQQNF---------- 543
            .|.|:|...   .||: ...|..|.:.:|      |:     |.|..|:..||.:
Zfish   542 THHEIRHNIQKELCLD-GTDGAMVRLEEC------QY-----KGHNTITSPQQKWELREDQLFYN 594

  Fly   544 ---RHCLEAQPELNAVTSSVCDPKNHKQQWKF 572
               :.||.|:||..::..  |:|.:..|.|.|
Zfish   595 KASKQCLSARPENPSLVP--CNPDDKYQLWLF 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant8	NP_648800.1	pp-GalNAc-T	131..430	CDD:133004	124/320 (39%)
		beta-trefoil_Ricin_Pgant8-like	445..573	CDD:467339	34/146 (23%)
galnt3	XP_021334717.1	pp-GalNAc-T	182..487	CDD:133004	124/320 (39%)
		beta-trefoil_Ricin_GALNT3	496..625	CDD:467346	35/150 (23%)