DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and GALNT14

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_016860395.1	Gene:	GALNT14 / 79623	HGNCID:	22946	Length:	563	Species:	Homo sapiens

Alignment Length:	499	Identity:	144/499 - (28%)
Similarity:	227/499 - (45%)	Gaps:	66/499 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTSP 80
            |.:|...||||...|.:.|.|..:|..:.|.::...| ||:|....|...||||.|.||:.:|..
Human    88 YAFNQRESERISSNRAIPDTRHLRCTLLVYCTDLPPT-SIIITFHNEARSTLLRTIRSVLNRTPT 151

  Fly    81 YLLKEIVLVHDGHPDLDLIRHIHHKLPIVIQLEMESSKGIIHARLTGAGVATGDILVFLNGHMEV 145
            :|::||:||.|...|.|..:.: .|||.|..|.....:|::.:|:.||.:|.|..|.||:.|.||
Human   152 HLIREIILVDDFSNDPDDCKQL-IKLPKVKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEV 215

  Fly   146 TRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLAFDWQLDHIFLPLDQHSWNSL- 209
            .|.||.|||..:..:...|..|::|.|:.::|.|.:.....:..|||.|        ...|..|
Human   216 NRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFTYIESASELRGGFDWSL--------HFQWEQLS 272

  Fly   210 ----------PKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILAV 264
                      .:|..:..:.|.:|.||:.||.:||.:|..:..:||:..|:|.:||.|||.:..|
Human   273 PEQKARRLDPTEPIRTPIIAGGLFVIDKAWFDYLGKYDMDMDIWGGENFEISFRVWMCGGSLEIV 337

  Fly   265 PCSRVGIIYKRDELEAQMAPNRNPSLQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNLTAESLDKP 329
            ||||||.::::.  ...:.|:.|.:..: ||.||..:||:||||.::|...|........:::..
Human   338 PCSRVGHVFRKK--HPYVFPDGNANTYI-KNTKRTAEVWMDEYKQYYYAARPFALERPFGNVESR 399

  Fly   330 RDLRRRLNCKSFEWYRSQVAPQI---------------RNHFLHAGLTN---YPIGKIMPFVAPH 376
            .|||:.|.|:||:||...:.|::               |...|.:...|   .|..|:.|
Human   400 LDLRKNLRCQSFKWYLENIYPELSIPKESSIQKGNIRQRQKCLESQRQNNQETPNLKLSP----- 459

  Fly   377 FCLSIKGGFPVIRKCHSTNFEDWTLTSRCQLKHGNMCLDVDY---KNNVRATKCTKKLSKNPWHY 438
             |..:||        .....:.|..|...|:....:||.|..   ...|....|.....:..|..
Human   460 -CAKVKG--------EDAKSQVWAFTYTQQILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTK 515

  Fly   439 NYQHSSFVSNGNKCLQIDV------NKVGLILSACDSDVTEQRW 476
            ...|...::: :.||..|:      |...::::.|:|.:..|.|
Human   516 TGSHIEHIAS-HLCLDTDMFGDGTENGKEIVVNPCESSLMSQHW 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	99/294 (34%)
		pp-GalNAc-T	54..349	CDD:133004	104/305 (34%)
		RICIN	367..478	CDD:238092	23/119 (19%)
		Ricin_B_lectin	373..476	CDD:279046	20/111 (18%)
GALNT14	XP_016860395.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810