DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7579 and galnt12

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_688194.1	Gene:	galnt12 / 559736	ZFINID:	ZDB-GENE-060503-704	Length:	578	Species:	Danio rerio

Alignment Length:	522	Identity:	158/522 - (30%)
Similarity:	237/522 - (45%)	Gaps:	98/522 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQT 78
            :|:|.|.::|:||.|.|.|.:..:|.|..:.|......|.|:|||...|...||||.::||: :|
Zfish    94 KKHQINTYVSDRISLHRRLAERWNPLCRNLKYDYLSLPTTSVVIAFYNEAWSTLLRTVHSVL-ET 157

  Fly    79 SP-YLLKEIVLVHDGHPDLDLIRHIHHKLPI---------VIQLEMESSKGIIHARLTGAGVATG 133
            || .||.|::|| |.:.|.:     |.|.|:         |..:.....:|::.|||.||.:|||
Zfish   158 SPDLLLNEVILV-DDYSDRE-----HLKEPLENYIADLKKVRLIRARKREGLVRARLLGASIATG 216

  Fly   134 DILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAY-RKLVEPEQLAFDWQLDHI 197
            ::|.||:.|.|...|||.|||:.|......|..|::|.|...:|.| ....||:...|||:|  :
Zfish   217 EVLTFLDCHCECHEGWLEPLLQRIKEEPSAVVCPVIDVIDWNTFQYLGNPGEPQIGGFDWRL--V 279

  Fly   198 FLPLDQHSWNSLPK-----------PYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELS 251
            |      :|:|:|:           ...|..:.|.:||:::|:|.:||.:|.|:..:||:.||.|
Zfish   280 F------TWHSIPEHEQKRRSAATDVVRSPTMAGGLFAVNKKYFLYLGTYDTGMEVWGGENLEFS 338

  Fly   252 LKVWQCGGLILAVPCSRVGIIYKRDELEAQMAP-NRNPSLQVQKNFKRVVDVWLDEYKLHFYRYN 315
            .::|||||.:...|||.||.::.:      .|| :||.:|   .|..|..:||:|::|..:|..:
Zfish   339 FRIWQCGGSLEIHPCSHVGHVFPK------KAPYSRNKAL---ANSVRAAEVWMDDFKEVYYHRS 394

  Fly   316 PKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIR---------NHFLHAGLTNYPIGKIMP 371
            |..|......:...|.||.||.||.|.|:...:.|.|:         ....:.|:|||
Zfish   395 PHARLEAYGDVTDRRKLRMRLRCKDFRWFLDNIYPDIQVPEDKPGMFGMLKNKGMTNY------- 452

  Fly   372 FVAPHFCL--------SIKGGFPVIRKCHSTN----FEDWTLTS-RCQLKHGNMCLDVD-YKNNV 422
                  |.        .|.|...::..||...    ||..||.. |...:....|:..| ....:
Zfish   453 ------CFDYNPPDEHKIAGHRVILYPCHGMGQNQFFEYSTLQEIRYNTRDPAGCVVADPVSTFL 511

  Fly   423 RATKCTKKLSKNPWHYNYQHSSFVSNGN-------KCLQ----IDVNKVGLILSACDSDVTEQRW 476
            ....|:|.....|   ..|...|..:|:       ||::    .|....|..|..| ||...|:|
Zfish   512 TMNLCSKPREAVP---EDQKFLFREDGSLYHVQTQKCVEAVDRTDAGSPGPALRPC-SDSDAQKW 572

  Fly   477 MF 478
            .|
Zfish   573 FF 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	105/306 (34%)
		pp-GalNAc-T	54..349	CDD:133004	110/317 (35%)
		RICIN	367..478	CDD:238092	28/135 (21%)
		Ricin_B_lectin	373..476	CDD:279046	27/127 (21%)
galnt12	XP_688194.1	pp-GalNAc-T	134..428	CDD:133004	110/317 (35%)
		Ricin_B_lectin	440..572	CDD:279046	31/148 (21%)
		RICIN	442..574	CDD:238092	32/148 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810